NLRR4 Activators

NLRR4, or Neural leucine-rich repeat protein 4, is a protein encoded by the NLRR4 gene in humans. As a member of the leucine-rich repeat (LRR) family of proteins, NLRR4 is characterized by the presence of a domain consisting of multiple repeats of the leucine-rich sequence, which is known to mediate protein-protein interactions.The LRR domain is a versatile structural motif involved in the formation of various functional complexes, and it plays a critical role in signal transduction, cell adhesion, and immune responses. Proteins containing LRRs are involved in diverse biological processes, including the development and functioning of the nervous system.

While the specific function of NLRR4 is not completely understood, it is believed to be involved in neural development and cellular communication in the nervous system. Its expression in neural tissues suggests that it may contribute to the formation or maintenance of neural circuits, possibly by influencing synapse formation and plasticity.Given its structural features, NLRR4 may act as a receptor or a cell-surface molecule that interacts with extracellular matrix components or other cell-surface proteins, thereby influencing cell migration, differentiation, or survival. These functions are critical during the development of the nervous system, where precise cellular organization and connectivity are essential for proper function.