Date published: 2025-12-22

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NHLRC3 Activators

NHLRC3, standing for NCL-1, HT2A, and LIN-41 domain-containing protein 3, is a protein encoded by the NHLRC3 gene in humans. The protein belongs to a broader family of proteins characterized by the presence of the NHL domain, which is typically associated with functions in protein-protein interactions and regulation of gene expression.Although the specific biological roles of NHLRC3 are not yet fully elucidated, its structural features suggest that it might be involved in cellular processes such as the regulation of development, differentiation, and apoptosis. Proteins with NHL domains have been found to play roles in a variety of biological contexts, often linked to the post-transcriptional regulation of gene expression, including the modulation of mRNA stability and translation, as well as in the ubiquitin-proteasome system.

Given the functional diversity of NHL domain-containing proteins, NHLRC3 may participate in similar regulatory networks. It could potentially be involved in the determination of cell fate, neuronal development, and the maintenance of cell type-specific functions, as evidenced by other well-characterized members of this protein family. Additionally, the protein may interact with other cellular components to modulate signaling pathways or contribute to the formation of multiprotein complexes that execute various cellular tasks.

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