NF-1A activators belong to a specific chemical class of compounds that are primarily recognized for their ability to modulate the activity of the NF-1A protein, also known as Nuclear Factor-1A. NF-1A is a transcription factor that plays a crucial role in the regulation of gene expression in various organisms, including humans. It is essential for the precise control of gene transcription and has been implicated in a wide range of cellular processes, including development, differentiation, and immune response. NF-1A activators are compounds that have been designed or identified to enhance the activity of this transcription factor, often by binding to specific regions of the NF-1A protein or its associated regulatory elements in the genome.
These activators are of significant interest to researchers in the fields of molecular biology and genetics because they provide a valuable tool for studying the intricate mechanisms of gene regulation. By selectively modulating the activity of NF-1A, researchers can gain insights into the genes and pathways controlled by this transcription factor, which may have broad implications for understanding various biological processes and diseases. NF-1A activators can also serve as potential leads for the development of more specific compounds that can fine-tune gene expression for various purposes, such as in the context of genetic engineering or synthetic biology. In summary, NF-1A activators represent a class of chemical compounds with the capacity to influence gene regulation by targeting the NF-1A transcription factor, offering valuable insights into the intricate world of molecular biology and genetic control mechanisms.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
This is a histone deacetylase inhibitor, known to alter chromatin structure and influence gene expression. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A PI3K/Akt pathway inhibitor, which can modulate various cellular processes including cell survival and proliferation. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
A MAPK pathway inhibitor, used to study signal transduction and gene expression. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $63.00 $182.00 | 8 | |
A major estrogen steroid hormone, known to bind estrogen receptors and influence gene expression. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
A synthetic glucocorticoid, used to study anti-inflammatory effects and glucocorticoid receptor-mediated gene expression. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc ions are essential for numerous biological functions, including the activity of various enzymes and transcription factors. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
An activator of adenylate cyclase, known to increase levels of cAMP and activate PKA, influencing various cellular processes. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $120.00 $326.00 $634.00 $947.00 $1259.00 | 38 | |
A PPARγ agonist, used to study adipogenesis and insulin sensitivity. | ||||||