Date published: 2026-3-10

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Nectin 1 Inhibitors

Nectin 1 inhibitors represent a class of compounds that target a specific cellular protein known as nectin 1. Nectin 1 is a cell adhesion molecule that plays a crucial role in various physiological processes, primarily by mediating cell-cell interactions. It is a member of the nectin family of immunoglobulin-like cell adhesion molecules, which are primarily expressed in epithelial and neuronal tissues. Nectin 1 is involved in the formation and maintenance of adherens junctions, which are essential for the structural integrity of tissues and the regulation of cell signaling pathways. Chemically, nectin 1 inhibitors can take various forms, including small organic molecules and peptides. These inhibitors are designed to disrupt the binding of nectin 1 to its cellular partners, such as other nectins or cadherins. By interfering with these interactions, nectin 1 inhibitors can modulate cell adhesion and signaling processes. This class of compounds has gained attention in both basic research and applications due to its ability to influence cell behavior and tissue organization. Researchers are exploring the structural and functional properties of nectin 1 inhibitors to better understand their mechanisms of action and implications in various biological contexts. In summary, nectin 1 inhibitors are chemical compounds that target the cell adhesion molecule nectin 1. By interfering with nectin 1's interactions, these inhibitors modulate cell adhesion and signaling processes, which could have broad implications in various biological contexts. Researchers continue to investigate the properties and mechanisms of action of nectin 1 inhibitors to unlock their full ability in understanding cellular processes and developing novel interventions in the future.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$218.00
$322.00
$426.00
7
(1)

This compound, also known as Decitabine, is a cytidine analog that incorporates into DNA and inhibits DNA methyltransferases, potentially leading to reduced methylation of the Nectin-1 promoter and decreased expression.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

Trichostatin A is a histone deacetylase inhibitor that can alter chromatin structure and increase the accessibility of transcriptional machinery to the Nectin-1 gene, potentially reducing its expression.

Valproic Acid

99-66-1sc-213144
10 g
$87.00
9
(1)

Valproic acid is another histone deacetylase inhibitor that may affect chromatin structure and modulate Nectin-1 gene expression.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin has been shown to down-regulate the expression of various genes through its anti-inflammatory and antioxidant properties, potentially impacting Nectin-1 expression.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

This compound, commonly found in green tea, has anti-inflammatory and anticancer properties, and it may modulate gene expression, including that of Nectin-1.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol is known for its anti-inflammatory and antioxidant properties, which could contribute to the down-regulation of Nectin-1 expression.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$153.00
$292.00
$489.00
$1325.00
$8465.00
$933.00
22
(1)

DL-Sulforaphane is a compound found in cruciferous vegetables that has been shown to modulate gene expression and may impact Nectin-1 expression.

3,3′-Diindolylmethane

1968-05-4sc-204624
sc-204624A
sc-204624B
sc-204624C
sc-204624D
sc-204624E
100 mg
500 mg
5 g
10 g
50 g
1 g
$37.00
$65.00
$89.00
$421.00
$681.00
$66.00
8
(1)

3,3'-Diindolylmethane (DIM) is a compound found in the digestion of indole-3-carbinol, found in cruciferous vegetables, and has been shown to modulate gene expression, potentially affecting Nectin-1.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

Quercetin is a flavonoid with anti-inflammatory and antioxidant properties that may influence the expression of various genes, including Nectin-1.