Date published: 2025-12-16

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Myotrophin Inhibitors

Myotrophin inhibitors represent a distinctive chemical class that exerts influence over cellular processes associated with muscle growth and development. At the core of their mechanism lies an intricate interplay with myotrophin, a protein intricately involved in muscle regulation. Myotrophin itself is recognized for its pivotal role in signaling cascades that orchestrate skeletal muscle hypertrophy, a process characterized by an increase in muscle cell size. The inhibitors are meticulously designed to impede the actions of myotrophin, disrupting the finely tuned pathways that dictate muscle fiber size and function.

Myotrophin inhibitors typically exhibit a specific structural motif that enables selective binding to myotrophin, inhibiting its interaction with key cellular components. This binding event can interfere with downstream signaling pathways that normally lead to increased protein synthesis and cellular growth within muscle tissues. By modulating myotrophin-mediated processes, these inhibitors provide a means to manipulate muscle development at a molecular level. Researchers and pharmacologists keenly explore the potential applications of myotrophin inhibitors in understanding fundamental aspects of muscle biology, recognizing their capacity to unveil the intricacies of cellular mechanisms governing muscle size and maintenance.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Cyclosporin A

59865-13-3sc-3503
sc-3503-CW
sc-3503A
sc-3503B
sc-3503C
sc-3503D
100 mg
100 mg
500 mg
10 g
25 g
100 g
$62.00
$90.00
$299.00
$475.00
$1015.00
$2099.00
69
(5)

Binds to cyclophilin and inhibits calcineurin, thereby reducing NFAT activation.

FK-506

104987-11-3sc-24649
sc-24649A
5 mg
10 mg
$76.00
$148.00
9
(1)

Forms a complex with FKBP12, inhibits calcineurin, and decreases NFAT dephosphorylation.

Valsartan

137862-53-4sc-220362
sc-220362A
sc-220362B
10 mg
100 mg
1 g
$39.00
$90.00
$120.00
4
(1)

Angiotensin II receptor blocker that can modulate effects on cardiac hypertrophy.

Losartan

114798-26-4sc-353662
100 mg
$127.00
18
(1)

Another angiotensin receptor blocker, reduces stress signaling in cardiomyocytes.

1-[4-(2-methoxyethyl)phenoxy]-3-propan-2-ylamino-propan-2-ol

51384-51-1sc-264643
2.5 g
$102.00
(1)

Beta-blocker that can reduce the stress on the heart and influence hypertrophy signals.

Propranolol

525-66-6sc-507425
100 mg
$180.00
(0)

A non-selective beta-blocker that can affect signaling pathways involved in hypertrophy.

Spironolactone

52-01-7sc-204294
50 mg
$107.00
3
(1)

Aldosterone antagonist, can lead to decreased fibrosis and hypertrophic signaling.

Candesartan

139481-59-7sc-217825
sc-217825B
sc-217825A
10 mg
100 mg
1 g
$46.00
$92.00
$148.00
6
(1)

Angiotensin receptor blocker that can modulate hypertrophic signaling.

Carvedilol

72956-09-3sc-200157
sc-200157A
sc-200157B
sc-200157C
sc-200157D
100 mg
1 g
10 g
25 g
100 g
$122.00
$235.00
$520.00
$979.00
$1500.00
2
(1)

Beta-blocker with alpha-blocking activity, affects signaling in cardiac hypertrophy.

Diltiazem

42399-41-7sc-204726
sc-204726A
1 g
5 g
$209.00
$464.00
4
(1)

Another calcium channel blocker that influences calcium signaling in cardiomyocytes.