Myotrophin inhibitors represent a distinctive chemical class that exerts influence over cellular processes associated with muscle growth and development. At the core of their mechanism lies an intricate interplay with myotrophin, a protein intricately involved in muscle regulation. Myotrophin itself is recognized for its pivotal role in signaling cascades that orchestrate skeletal muscle hypertrophy, a process characterized by an increase in muscle cell size. The inhibitors are meticulously designed to impede the actions of myotrophin, disrupting the finely tuned pathways that dictate muscle fiber size and function.
Myotrophin inhibitors typically exhibit a specific structural motif that enables selective binding to myotrophin, inhibiting its interaction with key cellular components. This binding event can interfere with downstream signaling pathways that normally lead to increased protein synthesis and cellular growth within muscle tissues. By modulating myotrophin-mediated processes, these inhibitors provide a means to manipulate muscle development at a molecular level. Researchers and pharmacologists keenly explore the potential applications of myotrophin inhibitors in understanding fundamental aspects of muscle biology, recognizing their capacity to unveil the intricacies of cellular mechanisms governing muscle size and maintenance.
SEE ALSO...
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
Binds to cyclophilin and inhibits calcineurin, thereby reducing NFAT activation. | ||||||
FK-506 | 104987-11-3 | sc-24649 sc-24649A | 5 mg 10 mg | $76.00 $148.00 | 9 | |
Forms a complex with FKBP12, inhibits calcineurin, and decreases NFAT dephosphorylation. | ||||||
Valsartan | 137862-53-4 | sc-220362 sc-220362A sc-220362B | 10 mg 100 mg 1 g | $39.00 $90.00 $120.00 | 4 | |
Angiotensin II receptor blocker that can modulate effects on cardiac hypertrophy. | ||||||
Losartan | 114798-26-4 | sc-353662 | 100 mg | $127.00 | 18 | |
Another angiotensin receptor blocker, reduces stress signaling in cardiomyocytes. | ||||||
1-[4-(2-methoxyethyl)phenoxy]-3-propan-2-ylamino-propan-2-ol | 51384-51-1 | sc-264643 | 2.5 g | $102.00 | ||
Beta-blocker that can reduce the stress on the heart and influence hypertrophy signals. | ||||||
Propranolol | 525-66-6 | sc-507425 | 100 mg | $180.00 | ||
A non-selective beta-blocker that can affect signaling pathways involved in hypertrophy. | ||||||
Spironolactone | 52-01-7 | sc-204294 | 50 mg | $107.00 | 3 | |
Aldosterone antagonist, can lead to decreased fibrosis and hypertrophic signaling. | ||||||
Candesartan | 139481-59-7 | sc-217825 sc-217825B sc-217825A | 10 mg 100 mg 1 g | $46.00 $92.00 $148.00 | 6 | |
Angiotensin receptor blocker that can modulate hypertrophic signaling. | ||||||
Carvedilol | 72956-09-3 | sc-200157 sc-200157A sc-200157B sc-200157C sc-200157D | 100 mg 1 g 10 g 25 g 100 g | $122.00 $235.00 $520.00 $979.00 $1500.00 | 2 | |
Beta-blocker with alpha-blocking activity, affects signaling in cardiac hypertrophy. | ||||||
Diltiazem | 42399-41-7 | sc-204726 sc-204726A | 1 g 5 g | $209.00 $464.00 | 4 | |
Another calcium channel blocker that influences calcium signaling in cardiomyocytes. | ||||||