Myopodin Inhibitors
Myopodin inhibitors work by affecting specific biochemical or cellular pathways where Myopodin is involved. These inhibitors target phosphorylation events and signaling pathways that Myopodin partakes in, thereby reducing its functional activity. Staurosporine, Genistein, PP2, and SU6656 are kinase inhibitors that can alter Myopodin's function by influencing the phosphorylation state or impacting signaling pathways related to cytoskeletal dynamics. LY294002 and Wortmannin, as PI3K inhibitors, can affect the functional activity of Myopodin by inhibiting PI3K-associated signaling pathways. U73122 is a phospholipase C inhibitor that can affect the functional activity of Myopodin by inhibiting phospholipase C-associated signal transduction processes.
Y-27632, a ROCK inhibitor, influences the functional activity of Myopodin, which is part of these pathways. PD98059 is an ERK inhibitor that can affect the functional activity of Myopodin by inhibiting the ERK pathway, while SP600125, a JNK inhibitor, and SB203580, a p38 MAP kinase inhibitor, function by inhibitingtheir respective kinases, thereby impacting the functional role of Myopodin in cytoskeletal dynamics. BAPTA-AM, a calcium chelator, affects Myopodin's functional activity by reducing intracellular calcium levels, thereby inhibiting calcium-dependent signal transduction processes where Myopodin is involved. In summary, these inhibitors can suppress the functional activity of Myopodin by interfering with its role in specific signaling pathways or biological processes related to cytoskeletal dynamics and cellular signal transduction.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Staurosporine is a broad-spectrum protein kinase inhibitor. Myopodin, a cytoskeletal protein, can be phosphorylated, thereby influencing its function. Staurosporine can inhibit the phosphorylation of Myopodin, affecting its interaction with actin and other cytoskeletal components. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein is a tyrosine kinase inhibitor. Tyrosine kinase can phosphorylate Myopodin, altering its function. Genistein, by inhibiting tyrosine kinase, can therefore hinder functional activity of Myopodin. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor. PI3K is involved in several signaling pathways that affect cytoskeletal dynamics, where Myopodin is a key regulator. The inhibition of PI3K by LY294002 can therefore disrupt Myopodin's functional activity. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is a potent PI3K inhibitor. By inhibiting PI3K, which is involved in signaling pathways influencing cytoskeletal dynamics, Wortmannin can disrupt the role of Myopodin in these processes. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
Y-27632 is a ROCK inhibitor. As Rho-associated coiled-coil forming kinase (ROCK) is involved in various signaling pathways controlling actin cytoskeleton, its inhibition can influence the functional activity of Myopodin. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is an ERK inhibitor. The ERK pathway is involved in various cellular processes including cytoskeletal dynamics. Its inhibition can impact the functional role of Myopodin in these processes. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is a JNK inhibitor. JNK pathways are involved in various cellular processes, including cytoskeletal dynamics. Its inhibition can impact the functional role of Myopodin in these processes. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a p38 MAP kinase inhibitor. The p38 MAP kinase is involved in various signaling pathways, including those controlling cytoskeletal dynamics. Its inhibition can disrupt Myopodin's functional role in these processes. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $92.00 $223.00 | 30 | |
PP2 is an Src family tyrosine kinase inhibitor. The Src family kinases are involved in various signaling pathways, including those involved in cytoskeletal dynamics. Their inhibition can impact the functional role of Myopodin in these processes. | ||||||
SU6656 | 330161-87-0 | sc-203286 sc-203286A | 1 mg 5 mg | $56.00 $130.00 | 27 | |
SU6656 is a selective Src family kinase inhibitor. The Src family kinases are involved in various signaling pathways, including those involving cytoskeletal dynamics. Their inhibition can impact the functional role of Myopodin in these processes. | ||||||