Mucin 8 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $33.00 $73.00 $265.00 $112.00 | 34 | |
N-Acetyl-L-cysteine (NAC) is a derivative of the amino acid L-cysteine. It acts as a mucolytic agent by breaking down disulfide bonds within mucus, thereby reducing its viscosity. NAC can potentially inhibit Mucin 8 by altering the physical properties of mucus and affecting its ability to form a protective barrier. | ||||||
Benzyl alcohol | 100-51-6 | sc-326216B sc-326216 sc-326216A | 250 ml 1 L 5 L | $31.00 $102.00 $408.00 | ||
Benzyl alcohol is a solvent and preservative commonly used in pharmaceutical formulations. It has been shown to disrupt the assembly and secretion of mucins, including Mucin 8, by interfering with the post-translational processing and glycosylation of mucin proteins. | ||||||
Sodium metabisulfite | 7681-57-4 | sc-203389 sc-203389A sc-203389B | 500 g 2.5 kg 5 kg | $24.00 $87.00 $91.00 | ||
Sodium metabisulfite is a food preservative and antioxidant that can inhibit Mucin 8 by targeting the sulfhydryl groups present in mucin proteins. It can potentially disrupt the structure and function of Mucin 8 by oxidizing and modifying the cysteine residues. | ||||||
Leupeptin hemisulfate | 103476-89-7 | sc-295358 sc-295358A sc-295358D sc-295358E sc-295358B sc-295358C | 5 mg 25 mg 50 mg 100 mg 500 mg 10 mg | $72.00 $145.00 $265.00 $489.00 $1399.00 $99.00 | 19 | |
Protease inhibitors, such as Leupeptin, Hemisulfate, can inhibit Mucin 8 by preventing the activity of proteases that degrade mucin proteins. By blocking the proteolytic degradation of Mucin 8, these inhibitors can potentially enhance its stability and abundance. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Histone deacetylase inhibitors, like trichostatin A, can potentially inhibit Mucin 8 by modulating the acetylation status of histones and other proteins involved in gene expression. Mucin 8 expression is regulated by epigenetic mechanisms, and histone deacetylase inhibitors can potentially alter the chromatin structure and accessibility of the Mucin 8 gene, leading to changes in its expression. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $61.00 $83.00 $349.00 | 155 | |
NF-κB is a transcription factor involved in the regulation of inflammatory responses. Mucin 8 expression can be induced by inflammatory stimuli through NF-κB activation. Inhibitors targeting NF-κB, like Bay 11-7082, can potentially inhibit Mucin 8 by blocking NF-κB-mediated transcriptional activation of the Mucin 8 gene. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $30.00 $52.00 $122.00 $367.00 | 25 | |
Brefeldin A inhibits protein transport from the endoplasmic reticulum to the Golgi apparatus, potentially affecting the processing and secretion of Mucin 8. | ||||||
Lactose | 63-42-3 | sc-221828A sc-221828 sc-221828B | 500 g 1 kg 2.5 kg | $107.00 $157.00 $345.00 | 1 | |
Lactose can competitively inhibit the binding of mucins, including Mucin 8, to pathogens or other ligands, potentially interfering with their protective functions. | ||||||