Mtvr2 Inhibitors
Chemical inhibitors of Mtvr2 can exert their effects through various mechanisms involving the modulation of neurotransmitter systems and their associated intracellular signaling pathways. Chlorpromazine, a dopamine antagonist, can inhibit Mtvr2 by altering neuronal activity and signaling pathways that involve this protein, thereby inhibiting its function within the central nervous system. Similarly, Haloperidol can inhibit Mtvr2 by reducing dopaminergic neurotransmission, which could alter intracellular signaling pathways involving Mtvr2, leading to functional inhibition. SCH-23390, as a selective dopamine D1 receptor antagonist, can disrupt the downstream signaling pathways that incorporate Mtvr2, inhibiting its neuronal function. Raclopride and Sulpiride, both selective dopamine D2 receptor antagonists, can alter dopaminergic signaling and the subsequent intracellular pathways that Mtvr2 is involved in, thereby inhibiting its function.
Furthermore, Spiperone acts as a potent antagonist of dopamine D2 and serotonin receptors, which can disrupt signaling pathways and inhibit Mtvr2's function. Tiapride, by targeting dopamine D2 and D3 receptors, can similarly inhibit the protein by altering the dopaminergic system and the downstream pathways where Mtvr2 is active. Amisulpride's antagonism at dopamine D2 and D3 receptors can disrupt dopaminergic neurotransmission and inhibit Mtvr2's activity. Aripiprazole, with its unique profile as a partial agonist at D2 receptors, can alter dopaminergic activity and inhibit Mtvr2 function depending on the neurotransmitter environment. Tetrabenazine and Reserpine, both VMAT2 inhibitors, can deplete monoamine neurotransmitters and disrupt neuronal signaling pathways, potentially inhibiting the functional role of Mtvr2. Lastly, Methylene Blue, by inhibiting nitric oxide synthase and guanylate cyclase, can influence signaling pathways involving neuronal processes, which could result in the functional inhibition of Mtvr2 within these pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Chlorpromazine | 50-53-3 | sc-357313 sc-357313A | 5 g 25 g | $60.00 $108.00 | 21 | |
Chlorpromazine is a dopamine antagonist that can inhibit dopamine receptors within the brain. Given that Mtvr2 is expressed in neurons, the blockade of dopamine receptors could lead to an alteration in neuronal activity and signaling pathways that may include Mtvr2, thus inhibiting its function. | ||||||
Haloperidol | 52-86-8 | sc-507512 | 5 g | $190.00 | ||
Haloperidol functions as a dopamine receptor antagonist. This chemical could inhibit Mtvr2 by reducing dopaminergic neurotransmission and altering the intracellular signaling pathways that Mtvr2 is part of, thereby inhibiting its neuronal function. | ||||||
SCH 23390 | 125941-87-9 | sc-200408 sc-200408A | 5 mg 25 mg | $175.00 $719.00 | 2 | |
SCH-23390 is a selective antagonist for the dopamine D1 receptor. By inhibiting this specific receptor subtype, the downstream signaling pathways that involve Mtvr2 could be inhibited, leading to a functional inhibition of Mtvr2 in those pathways. | ||||||
Raclopride | 84225-95-6 | sc-204229 sc-204229A | 10 mg 50 mg | $89.00 $295.00 | 2 | |
Raclopride is a selective dopamine D2 receptor antagonist. It can inhibit Mtvr2 by modulating the dopaminergic system and subsequent intracellular pathways where Mtvr2 is involved, resulting in the inhibition of Mtvr2's functionality within these pathways. | ||||||
(RS)-(±)-Sulpiride | 15676-16-1 | sc-205494 | 100 mg | $69.00 | ||
Sulpiride is a selective dopamine D2 receptor antagonist. It inhibits dopaminergic activity which could lead to the inhibition of downstream signaling that involves the functional activity of Mtvr2, thus inhibiting the protein. | ||||||
Spiperone | 749-02-0 | sc-471047 | 250 mg | $130.00 | ||
Spiperone acts as a potent antagonist of dopamine D2 receptors as well as serotonin receptors. By inhibiting these neurotransmitter systems, it could disrupt signaling pathways that involve Mtvr2, leading to functional inhibition of the protein. | ||||||
Aripiprazole | 129722-12-9 | sc-207300 sc-207300A sc-207300B | 100 mg 1 g 5 g | $175.00 $208.00 $1017.00 | 3 | |
Aripiprazole acts as a partial agonist at dopamine D2 receptors but can function as an antagonist in hyperdopaminergic states. This modulation of dopaminergic activity can lead to changes in intracellular signaling involving Mtvr2, resulting in functional inhibition. | ||||||
Tetrabenazine | 58-46-8 | sc-204338 sc-204338A | 10 mg 50 mg | $165.00 $707.00 | ||
Tetrabenazine inhibits vesicular monoamine transporter 2 (VMAT2) and can deplete monoamine neurotransmitters. This depletion could disrupt neuronal signaling pathways and neurotransmitter balance, potentially inhibiting Mtvr2's function in these pathways. | ||||||
Reserpine | 50-55-5 | sc-203370 sc-203370A | 1 g 5 g | $134.00 $406.00 | 1 | |
Reserpine is an inhibitor of VMAT2, leading to the depletion of monoamine neurotransmitters. The consequent changes in neuronal signaling could inhibit the functional role of Mtvr2 in these pathways. | ||||||
Methylene blue | 61-73-4 | sc-215381B sc-215381 sc-215381A | 25 g 100 g 500 g | $42.00 $102.00 $322.00 | 3 | |
Methylene Blue acts as an inhibitor of nitric oxide synthase and guanylate cyclase, potentially influencing various signaling pathways including those involving neuronal processes. This could result in the functional inhibition of Mtvr2 within these pathways. | ||||||