MRTF-B Inhibitors
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
CCG-1423 | 285986-88-1 | sc-205241 sc-205241A | 1 mg 5 mg | $30.00 $90.00 | 8 | |
CCG-1423 is a selective inhibitor of RhoA-mediated signaling, impeding the activation of MRTF-B. By disrupting the RhoA pathway, CCG-1423 modulates the cytoskeletal dynamics and prevents MRTF-B translocation to the nucleus, inhibiting its transcriptional activity. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Y-27632 acts as a ROCK (Rho-associated protein kinase) inhibitor, indirectly affecting MRTF-B through the Rho/ROCK pathway. By suppressing ROCK activity, Y-27632 impedes the downstream signaling that leads to MRTF-B activation, thereby inhibiting its transcriptional regulatory functions. | ||||||
CCG 203971 | 1443437-74-8 | sc-507360 | 10 mg | $89.00 | ||
CCG-203971 is a specific inhibitor of the serum response factor (SRF), a key regulator of MRTF-B activity. By targeting SRF, CCG-203971 disrupts the transcriptional complex involving MRTF-B, hindering its ability to modulate gene expression and participate in cellular processes. | ||||||
CK 666 | 442633-00-3 | sc-361151 sc-361151A | 10 mg 50 mg | $321.00 $1040.00 | 5 | |
CK-666 is an Arp2/3 complex inhibitor, disrupting actin polymerization and indirectly affecting MRTF-B function. By impeding the formation of branched actin networks, CK-666 interferes with the cytoskeletal dynamics that regulate MRTF-B activity, leading to inhibition of its transcriptional functions. | ||||||
BAPTA/AM | 126150-97-8 | sc-202488 sc-202488A | 25 mg 100 mg | $138.00 $458.00 | 61 | |
BAPTA-AM is a calcium chelator that indirectly influences MRTF-B by modulating intracellular calcium levels. By sequestering calcium ions, BAPTA-AM disrupts the signaling cascades involving calcium-dependent pathways, hindering MRTF-B activation and its subsequent transcriptional activities. | ||||||
CK-869 | 388592-44-7 | sc-507274 | 5 mg | $163.00 | ||
CK-869 is a selective inhibitor of the ARP2/3 complex, influencing MRTF-B through its impact on actin dynamics. By targeting the Arp2/3 complex, CK-869 disrupts actin polymerization, indirectly inhibiting MRTF-B translocation to the nucleus and its involvement in the transcriptional regulation of target genes. | ||||||
SMIFH2 | 340316-62-3 | sc-507273 | 5 mg | $140.00 | ||
SMIFH2 is a formin inhibitor that indirectly modulates MRTF-B through its impact on actin polymerization. By inhibiting formin activity, SMIFH2 disrupts the process of actin nucleation and polymerization, affecting the cytoskeletal dynamics that regulate MRTF-B activation and subsequent transcriptional functions. | ||||||
Wiskostatin | 253449-04-6 | sc-204399 sc-204399A sc-204399B sc-204399C | 1 mg 5 mg 25 mg 50 mg | $49.00 $124.00 $441.00 $828.00 | 4 | |
Wiskostatin is an inhibitor of the Wiskott-Aldrich syndrome protein (WASP), indirectly affecting MRTF-B through its role in actin polymerization. By inhibiting WASP, Wiskostatin disrupts the actin cytoskeleton, interfering with the signaling pathways that regulate MRTF-B activation and subsequent transcriptional functions. | ||||||