MRP-L52 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Oligomycin | 1404-19-9 | sc-203342 sc-203342C | 10 mg 1 g | $149.00 $12495.00 | 18 | |
Targets ATP synthase in mitochondria, leading to inhibition of ATP production. MRP-L52 is essential for mitochondrial protein synthesis, and a decrease in ATP levels impairs the energy-dependent processes of mitochondrial translation, indirectly inhibiting MRP-L52 function. | ||||||
Chloramphenicol | 56-75-7 | sc-3594 | 25 g | $90.00 | 10 | |
Binds to the peptidyl transferase component of the mitochondrial ribosome, directly inhibiting mitochondrial protein synthesis and, by extension, the function of MRP-L52. | ||||||
Erythromycin | 114-07-8 | sc-204742 sc-204742A sc-204742B sc-204742C | 5 g 25 g 100 g 1 kg | $57.00 $245.00 $831.00 $1331.00 | 4 | |
Interacts with the mitochondrial ribosome similarly to bacterial ribosomes, impeding mitochondrial translation. This can indirectly inhibit the function of MRP-L52, which is integral to the ribosomal structure and function. | ||||||
Doxycycline-d6 | 564-25-0 unlabeled | sc-218274 | 1 mg | $16500.00 | ||
Acts on the mitochondrial ribosome to inhibit protein synthesis, thereby indirectly inhibiting the function of MRP-L52, which is crucial for the mitochondrial protein synthesis machinery. | ||||||
3′-Azido-3′-deoxythymidine | 30516-87-1 | sc-203319 | 10 mg | $61.00 | 2 | |
Inhibits the enzyme thymidine kinase, which can lead to mitochondrial toxicity and dysregulation of mitochondrial DNA replication, indirectly affecting the function of MRP-L52 by disrupting the availability of encoded proteins that are essential for mitochondrial ribosome stability and function. | ||||||
Tetracycline | 60-54-8 | sc-205858 sc-205858A sc-205858B sc-205858C sc-205858D | 10 g 25 g 100 g 500 g 1 kg | $63.00 $94.00 $270.00 $417.00 $634.00 | 6 | |
Binds to the 16S rRNA of the mitochondrial ribosome and inhibits protein synthesis, affecting the functionality of MRP-L52 by compromising its role in ribosomal translation processes. | ||||||
Actinonin | 13434-13-4 | sc-201289 sc-201289B | 5 mg 10 mg | $170.00 $385.00 | 3 | |
Inhibits peptide deformylase, an enzyme involved in the maturation of nascent peptides during mitochondrial protein synthesis. This inhibition impacts the function of MRP-L52, as it is a component of the mitochondrial ribosome and its function is contingent upon proper peptide synthesis and processing. | ||||||
Antimycin A | 1397-94-0 | sc-202467 sc-202467A sc-202467B sc-202467C | 5 mg 10 mg 1 g 3 g | $55.00 $63.00 $1675.00 $4692.00 | 51 | |
Inhibits complex III of the mitochondrial electron transport chain, leading to decreased ATP production. This energy depletion indirectly inhibits the function of MRP-L52 by impairing mitochondrial translation, for which ATP is essential. | ||||||
ABT-199 | 1257044-40-8 | sc-472284 sc-472284A sc-472284B sc-472284C sc-472284D | 1 mg 5 mg 10 mg 100 mg 3 g | $118.00 $337.00 $520.00 $832.00 $1632.00 | 10 | |
Targets Bcl-2, an anti-apoptotic protein, leading to mitochondrial outer membrane permeabilization and potential release of factors that can impair mitochondrial function. Indirectly affects MRP-L52 by disrupting mitochondrial integrity, which is essential for its ribosomal function. | ||||||
Atovaquone | 95233-18-4 | sc-217675 | 10 mg | $270.00 | 2 | |
Inhibits cytochrome b within the mitochondrial electron transport chain, leading to a reduction in ATP synthesis. As mitochondrial translation is an ATP-dependent process, the inhibition of ATP production indirectly impacts the function of MRP-L52, which is a component of the mitochondrial ribosome and reliant on ATP for proper protein synthesis. | ||||||