MRP-L22 Activators
MRP-L22, also known as Mitochondrial Ribosomal Protein L22, is a protein that is encoded by the MRPL22 gene in humans. As its name suggests, MRP-L22 is a component of the mitochondrial ribosome, which is responsible for the synthesis of proteins within the mitochondria, the energy-producing organelles in cells.Mitochondrial ribosomes are different from their counterparts in the cytoplasm, both in structure and in the proteins they contain. MRP-L22 is part of the large subunit (39S) of the mitochondrial ribosome, which joins with the small subunit (28S) to form the complete ribosome.
MRP-L22, along with other mitochondrial ribosomal proteins, plays a critical role in the assembly and function of the mitochondrial ribosome. It contributes to the process of translating mitochondrial DNA-encoded mRNA sequences into proteins, most of which are essential components of the mitochondrial respiratory chain. This chain is responsible for oxidative phosphorylation, the process that generates the majority of the cell's ATP, the main source of cellular energy.Alterations in the MRPL22 gene or the MRP-L22 protein can affect mitochondrial function and lead to mitochondrial diseases.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Oligomycin | 1404-19-9 | sc-203342 sc-203342C | 10 mg 1 g | $149.00 $12495.00 | 18 | |
Oligomycin, an inhibitor of mitochondrial ATP synthase, can affect mitochondrial function, potentially impacting MRP-L22. | ||||||
Chloramphenicol | 56-75-7 | sc-3594 | 25 g | $90.00 | 10 | |
Chloramphenicol, an inhibitor of bacterial protein synthesis, can also affect mitochondrial ribosomes, potentially influencing MRP-L22. | ||||||
Doxycycline-d6 | 564-25-0 unlabeled | sc-218274 | 1 mg | $16500.00 | ||
Doxycycline, a tetracycline antibiotic, inhibits protein synthesis in mitochondria, which might affect MRP-L22 function. | ||||||
Azithromycin | 83905-01-5 | sc-254949 sc-254949A sc-254949B sc-254949C sc-254949D | 25 mg 50 mg 500 mg 1 g 5 g | $52.00 $103.00 $260.00 $364.00 $728.00 | 17 | |
Azithromycin, known to target bacterial ribosomes, may also influence mitochondrial ribosomes, affecting MRP-L22 activity. | ||||||
Erythromycin | 114-07-8 | sc-204742 sc-204742A sc-204742B sc-204742C | 5 g 25 g 100 g 1 kg | $57.00 $245.00 $831.00 $1331.00 | 4 | |
Erythromycin, another antibiotic affecting ribosomal function, can indirectly influence mitochondrial protein synthesis involving MRP-L22. | ||||||
Tigecycline | 220620-09-7 | sc-394197 sc-394197A | 5 mg 25 mg | $190.00 $448.00 | 1 | |
Tigecycline, a tetracycline derivative, inhibits protein synthesis and may affect mitochondrial ribosomes, impacting MRP-L22. | ||||||
Antimycin A | 1397-94-0 | sc-202467 sc-202467A sc-202467B sc-202467C | 5 mg 10 mg 1 g 3 g | $55.00 $63.00 $1675.00 $4692.00 | 51 | |
Antimycin A, an inhibitor of mitochondrial complex III, can affect mitochondrial respiration, potentially impacting MRP-L22. | ||||||