Date published: 2025-12-20

1-800-457-3801

SCBT Portrait Logo
Seach Input

MRP-L2 Inhibitors

MRP-L2 inhibitors are a class of chemical compounds that target and modulate the activity of MRP-L2 proteins. MRP-L2, which stands for Multidrug Resistance-Associated Protein-Like 2, is a member of the ATP-binding cassette (ABC) transporter superfamily. These transporters play a crucial role in the movement of various molecules across cell membranes. MRP-L2, specifically, is involved in the active transport of a wide range of substrates, including organic anions, peptides, and xenobiotics. The inhibitors that specifically target MRP-L2 are designed to bind to the protein and interfere with its function. By binding to MRP-L2, these inhibitors can either block the transport of substrates or modulate its activity in a way that affects the cellular processes involving this transporter. The precise mechanism of action of MRP-L2 inhibitors may vary depending on the specific compound, but their overall goal is to regulate the activity of MRP-L2. Research into MRP-L2 inhibitors is aimed at understanding the fundamental biological processes involving MRP-L2 and exploring applications in various fields. Scientists are particularly interested in elucidating the role of MRP-L2 in normal cellular physiology and pathological conditions. By developing inhibitors that can selectively target MRP-L2, researchers hope to gain insights into the intricate mechanisms of ABC transporters and uncover new avenues for intervention in cellular processes that rely on MRP-L2 activity.

Items 1 to 10 of 13 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Tigecycline

220620-09-7sc-394197
sc-394197A
5 mg
25 mg
$186.00
$439.00
1
(1)

Although primarily an antibiotic, tigecycline has been shown to inhibit MRPL2, leading to impaired mitochondrial protein synthesis. It has been studied for its potential anticancer effects due to its ability to affect mitochondrial function.

Erythromycin

114-07-8sc-204742
sc-204742A
sc-204742B
sc-204742C
5 g
25 g
100 g
1 kg
$56.00
$240.00
$815.00
$1305.00
4
(3)

Another antibiotic, erythromycin, has been found to inhibit MRPL2 and disrupt mitochondrial protein synthesis. It has been explored for its potential in cancer and other diseases associated with mitochondrial dysfunction.

Doxycycline-d6

564-25-0 unlabeledsc-218274
1 mg
$16500.00
(0)

Doxycycline, a commonly used antibiotic, has been shown to inhibit MRPL2, leading to the disruption of mitochondrial protein synthesis.

Valproic Acid

99-66-1sc-213144
10 g
$85.00
9
(1)

Valproic acid, an antiepileptic drug, has been shown to inhibit MRPL2 and disrupt mitochondrial protein synthesis. Its potential effects on mitochondrial dysfunction-related conditions have been explored, including neurodegenerative diseases and cancer.

Chloramphenicol

56-75-7sc-3594
25 g
$53.00
10
(1)

Chloramphenicol, an antibiotic, has been reported to inhibit MRPL2, leading to impaired mitochondrial protein synthesis. Its potential therapeutic applications have been studied, particularly in cancer research.

Gentamicin sulfate

1405-41-0sc-203334
sc-203334A
sc-203334F
sc-203334B
sc-203334C
sc-203334D
sc-203334E
1 g
5 g
50 g
100 g
1 kg
2.5 kg
7.5 kg
$55.00
$175.00
$499.00
$720.00
$1800.00
$2600.00
$6125.00
3
(1)

Gentamicin, an antibiotic from the aminoglycoside class, has been found to inhibit MRPLIts effects on mitochondrial function and potential therapeutic uses have been investigated, particularly in the context of mitochondrial diseases.

Azithromycin

83905-01-5sc-254949
sc-254949A
sc-254949B
sc-254949C
sc-254949D
25 mg
50 mg
500 mg
1 g
5 g
$51.00
$101.00
$255.00
$357.00
$714.00
17
(1)

Macrolide antibiotics have been reported to inhibit MRPL2 and interfere with mitochondrial protein synthesis. Their potential effects on mitochondrial dysfunction-related conditions have been studied.

Clarithromycin

81103-11-9sc-205634
sc-205634A
100 mg
250 mg
$75.00
$120.00
1
(1)

Macrolide antibiotics have been reported to inhibit MRPL2 and interfere with mitochondrial protein synthesis. Their potential effects on mitochondrial dysfunction-related conditions have been studied.

Pentamidine

100-33-4sc-208158
sc-208158A
25 mg
50 mg
$373.00
$557.00
(1)

Pentamidine, an antiparasitic agent in research, has been shown to inhibit MRPL2, resulting in impaired mitochondrial protein synthesis. Its potential effects on mitochondrial dysfunction-related diseases have been explored.

Roxithromycin

80214-83-1sc-205845
sc-205845A
1 g
5 g
$51.00
$153.00
(1)

Macrolide antibiotics have been reported to inhibit MRPL2 and interfere with mitochondrial protein synthesis. Their potential effects on mitochondrial dysfunction-related conditions have been studied.