| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
MRN-ATM Pathway Inhibitor, Mirin | 299953-00-7 | sc-203144 | 10 mg | $141.00 | 4 | |
MRN-ATM Pathway Inhibitor, Mirin, is a selective inhibitor of the MRE11 complex, crucial for DNA damage response. It disrupts the MRE11-RAD50-NBS1 complex, altering the kinetics of DNA repair pathways. By modulating the interaction between MRE11 and its substrates, Mirin influences the cellular response to genotoxic stress. Its unique binding affinity and specificity enable it to effectively hinder the homologous recombination repair process, showcasing its role in DNA integrity maintenance. | ||||||