Date published: 2026-4-25

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MRE11 Inhibitors

Santa Cruz Biotechnology now offers a broad range of MRE11 Inhibitors for use in various applications. MRE11 inhibitors are a class of chemicals that target the MRE11 protein, a critical component of the MRN complex (MRE11-RAD50-NBS1), which plays a pivotal role in the DNA damage response and repair mechanisms. These inhibitors are essential tools in the field of molecular biology and genetics, as they allow researchers to explore the intricacies of DNA repair pathways, particularly the process of homologous recombination and double-strand break repair. By inhibiting the function of MRE11, scientists can study the effects of impaired DNA repair, which is crucial for understanding genome stability, cellular responses to DNA damage, and the underlying mechanisms of various genetic disorders. Furthermore, MRE11 inhibitors are valuable in studying the interactions between DNA repair proteins and other cellular processes, providing insights into the complex network of cellular homeostasis. The availability of these inhibitors has significantly advanced research in genomics, cell biology, and biochemistry, offering a powerful toolset for dissecting the molecular underpinnings of DNA repair. View detailed information on our available MRE11 Inhibitors by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

MRN-ATM Pathway Inhibitor, Mirin

299953-00-7sc-203144
10 mg
$141.00
4
(1)

MRN-ATM Pathway Inhibitor, Mirin, is a selective inhibitor of the MRE11 complex, crucial for DNA damage response. It disrupts the MRE11-RAD50-NBS1 complex, altering the kinetics of DNA repair pathways. By modulating the interaction between MRE11 and its substrates, Mirin influences the cellular response to genotoxic stress. Its unique binding affinity and specificity enable it to effectively hinder the homologous recombination repair process, showcasing its role in DNA integrity maintenance.