MOF Activators
MOF Activators represent a diverse group of compounds that play a pivotal role in enhancing the functional activity of MOF (Males absent on the first). These activators, such as Mofezolac, MG-149, C646, TMP195, and EPZ004777, directly target the histone acetyltransferase activity of MOF. By specifically influencing MOF's catalytic function, these compounds promote histone acetylation, resulting in altered chromatin structure and heightened gene expression. This direct activation of MOF provides researchers with valuable tools to investigate its role in epigenetic regulation and cellular processes dependent on histone acetylation.
Additionally, MOF Activators include compounds like Sodium Butyrate, Trichostatin A, Valproic Acid, Sodium Valproate, Givinostat, Scriptaid, and SAHA, which indirectly enhance MOF activity by inhibiting histone deacetylases (HDACs). Through this indirect mechanism, these compounds modulate histone acetylation dynamics, influencing the equilibrium of histone modifications and subsequently impacting MOF-mediated epigenetic regulation. The versatility of MOF Activators offers researchers a comprehensive toolkit for probing the intricate mechanisms of histone acetylation and chromatin remodeling, contributing to a deeper understanding of epigenetic processes in cellular contexts.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
[3,4-Bis-(4-methoxyphenyl)isoxazol-5-yl]-acetic acid | 78967-07-4 | sc-313584A sc-313584 | 100 mg 250 mg | $153.00 $245.00 | ||
THis compound, also called Mofezolac, is a chemical compound that directly enhances the functional activity of MOF (Males absent on the first), a histone acetyltransferase. By specifically targeting the catalytic activity of MOF, Mofezolac promotes histone acetylation, resulting in altered chromatin structure and enhanced gene expression. This direct activation of MOF supports its role in epigenetic regulation, influencing cellular processes dependent on histone acetylation. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium Butyrate is a chemical compound that indirectly enhances the functional activity of MOF by inhibiting histone deacetylases (HDACs). By enhancing histone acetylation, Sodium Butyrate indirectly promotes MOF activity, leading to altered chromatin structure and enhanced gene expression. This compound serves as an indirect activator of MOF, influencing cellular processes through the modulation of histone acetylation dynamics. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Trichostatin A is a chemical compound that indirectly enhances the functional activity of MOF by inhibiting histone deacetylases (HDACs). By enhancing histone acetylation, Trichostatin A indirectly promotes MOF activity, leading to altered chromatin structure and enhanced gene expression. This compound serves as an indirect activator of MOF, influencing cellular processes through the modulation of histone acetylation dynamics. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
Valproic Acid is a chemical compound that indirectly enhances the functional activity of MOF by inhibiting histone deacetylases (HDACs). By enhancing histone acetylation, Valproic Acid indirectly promotes MOF activity, leading to altered chromatin structure and enhanced gene expression. This compound serves as an indirect activator of MOF, influencing cellular processes through the modulation of histone acetylation dynamics. | ||||||
ITF2357 | 732302-99-7 | sc-364513 sc-364513A | 5 mg 50 mg | $340.00 $1950.00 | ||
ITF2357 (Givinostat) is a chemical compound that indirectly enhances the functional activity of MOF by inhibiting histone deacetylases (HDACs). By enhancing histone acetylation, Givinostat indirectly promotes MOF activity, leading to altered chromatin structure and enhanced gene expression. This compound serves as an indirect activator of MOF, influencing cellular processes through the modulation of histone acetylation dynamics. | ||||||
Scriptaid | 287383-59-9 | sc-202807 sc-202807A | 1 mg 5 mg | $64.00 $183.00 | 11 | |
Scriptaid is a chemical compound that indirectly enhances the functional activity of MOF by inhibiting histone deacetylases (HDACs). By enhancing histone acetylation, Scriptaid indirectly promotes MOF activity, leading to altered chromatin structure and enhanced gene expression. This compound serves as an indirect activator of MOF, influencing cellular processes through the modulation of histone acetylation dynamics. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
SAHA is a chemical compound that indirectly enhances the functional activity of MOF by inhibiting histone deacetylases (HDACs). By enhancing histone acetylation, SAHA indirectly promotes MOF activity, leading to altered chromatin structure and enhanced gene expression. This compound serves as an indirect activator of MOF, influencing cellular processes through the modulation of histone acetylation dynamics. | ||||||