Date published: 2026-4-24

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MLH1 Antibodies

Santa Cruz Biotechnology features a diverse variety of MLH1 monoclonal antibodies for research focused on understanding MLH1's role in DNA mismatch repair and its implications in various cancers. MLH1 monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). MLH1 is a critical component of the DNA mismatch repair system, which helps maintain genomic stability by correcting errors that occur during DNA replication. Deficiencies in MLH1 function can lead to microsatellite instability and are associated with hereditary nonpolyposis colorectal cancer (Lynch syndrome). Understanding MLH1 expression and function is essential for elucidating its role in tumorigenesis and developing targeted therapies. MLH1 monoclonal antibodies enable researchers to investigate DNA repair mechanisms and molecular pathways involved in cancer development. Studying MLH1 can provide insights into potential therapeutic strategies for cancer treatment. Research with MLH1 monoclonal antibodies contributes to advancing our understanding of genomic stability and cancer biology. Santa Cruz Biotechnology MLH1 monoclonal antibodies support researchers worldwide in their pursuit of scientific discoveries that may lead to improved cancer treatments and diagnostic approaches.

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MLH1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

MLH1 Antibody (B-12)

sc-271978mouse IgG1 κ737-756 (h)WB, IP, IF, ELISAm, r, h
7
(15)

MLH1 Antibody (G168-15)

sc-56161mouse IgG1FL (h)WB, IP, IF, IHC(P), ELISAm, r, h
6
(4)

MLH1 Antibody (A-8)

sc-133228mouse IgG2a κ457-756 (h)WB, IP, IF, ELISAm, r, h
4
(3)

MLH1 Antibody (Clone 14)

sc-56160mouse IgG1FL (h)WB, IP, IF, IHC(P), ELISAh
2
(1)

MLH1 Antibody (D-2)

sc-166625mouse IgG1 κ457-756 (h)WB, IP, IF, ELISAm, r, h

new

(2)

MLH1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MLH1 CRISPR/Cas9 KO Plasmid (h)

sc-401276hGene KnockoutGFP0
(0)

MLH1 HDR Plasmid (h)

sc-401276-HDRhHomology Directed RepairPuromycin0
(0)

MLH1 Double Nickase Plasmid (h)

sc-401276-NIChGene KnockoutPuromycin0
(0)

MLH1 Double Nickase Plasmid (h2)

sc-401276-NIC-2hGene KnockoutPuromycin0
(0)

MLH1 CRISPR/Cas9 KO Plasmid (m)

sc-421660mGene KnockoutGFP0
(0)

MLH1 HDR Plasmid (m)

sc-421660-HDRmHomology Directed RepairPuromycin0
(0)

MLH1 Double Nickase Plasmid (m)

sc-421660-NICmGene KnockoutPuromycin0
(0)

MLH1 Double Nickase Plasmid (m2)

sc-421660-NIC-2mGene KnockoutPuromycin0
(0)

MLH1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MLH1 siRNA (h)

sc-35943hGene SilencingN/A
2
(0)

MLH1 shRNA Plasmid (h)

sc-35943-SHhGene SilencingPuromycin
2
(0)

MLH1 shRNA (h) Lentiviral Particles

sc-35943-VhGene SilencingPuromycin
2
(0)

MLH1 siRNA (m)

sc-35944mGene SilencingN/A0
(0)

MLH1 shRNA Plasmid (m)

sc-35944-SHmGene SilencingPuromycin0
(0)

MLH1 shRNA (m) Lentiviral Particles

sc-35944-VmGene SilencingPuromycin0
(0)