Met Inhibitors
Santa Cruz Biotechnology now offers a broad range of Met Inhibitors. MET (c-Met) is a proto-oncogene that encodes a protein known as hepatocyte growth factor receptor (HGFR). MET is a membrane receptor that is essential for embryonic development and wound healing. Cancer stem cells are thought to adopt the ability to express MET, and thus become the cause of cancer persistence. Met Inhibitors offered by Santa Cruz inhibit Met and, in some cases, other hepatocyte growth factor and tumor growth related proteins. View detailed Met Inhibitor specifications, including Met Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.
Items 21 to 22 of 22 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
BMS 794833 | 1174046-72-0 | sc-364439 sc-364439A | 10 mg 50 mg | $320.00 $970.00 | ||
BMS 794833 (CAS 1174046-72-0) is a chemical compound acting as a potent inhibitor of Met. It modulates Met activity, impacting cellular processes. The compound's effects on Met signaling have attracted interest in research due to its potential implications in various contexts. | ||||||
NVP-BVU972 | 1185763-69-2 | sc-364555 sc-364555A | 10 mg 50 mg | $555.00 $1606.00 | ||
NVP-BVU972 acts as a selective Met inhibitor, distinguished by its unique ability to disrupt dimerization of the Met receptor. This compound engages in specific electrostatic interactions that stabilize its binding to the receptor, effectively blocking downstream signaling pathways. Its kinetic profile reveals a rapid association and slower dissociation, contributing to prolonged inhibition. Furthermore, NVP-BVU972's lipophilicity enhances membrane permeability, facilitating its cellular uptake and interaction with target proteins. | ||||||