Mast Cell Protease 5 Activators
Mast cells play an essential role in the immune response, particularly in allergic reactions and inflammation. They store a variety of substances in their granules, including histamine and various enzymes. Upon activation, mast cells rapidly release these substances in a process known as degranulation.
MCP-5 is one of the enzymes released during degranulation. It belongs to the family of serine proteases, enzymes that cleave peptide bonds in proteins in response to a variety of signals. MCP-5 is a chymotryptic enzyme, meaning it preferentially cleaves proteins at aromatic amino acid residues.
The exact biological function of MCP-5 is not fully understood. Like other mast cell proteases, MCP-5 is believed to contribute to the immune response by cleaving and activating or inactivating various proteins and peptides. This can influence vascular permeability, tissue remodeling, and the activity of other immune cells.In the context of disease, MCP-5, as part of mast cell activity, can be involved in allergic reactions and certain inflammatory diseases. For example, elevated levels of mast cell proteases have been observed in asthma, a condition characterized by chronic inflammation of the airways.In summary, Mast Cell Protease 5 is a chymotryptic serine protease produced by mast cells, with a role in immune responses, including allergies and inflammation. Its precise functions and implications in disease are areas of active research.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cromolyn disodium salt | 15826-37-6 | sc-207459 sc-207459A sc-207459B sc-207459C sc-207459D sc-207459E sc-207459F | 1 g 5 g 25 g 50 g 100 g 500 g 1 kg | $50.00 $174.00 $624.00 $1040.00 $1873.00 $2913.00 $3537.00 | ||
Cromolyn Sodium inhibits mast cell degranulation, potentially affecting MCP-5 release in allergic responses. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin has anti-inflammatory properties and can stabilize mast cells, potentially influencing MCP-5 activity. | ||||||
Aspirin | 50-78-2 | sc-202471 sc-202471A | 5 g 50 g | $20.00 $42.00 | 4 | |
Aspirin modulates inflammatory pathways and could indirectly affect MCP-5 activity in certain contexts. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin has anti-inflammatory properties and may modulate mast cell-mediated responses, affecting MCP-5. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG, a major component of green tea, has anti-inflammatory effects and may influence MCP-5 activity. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol modulates several signaling pathways and could indirectly affect MCP-5 in inflammatory responses. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Dexamethasone, a corticosteroid, can modulate inflammation and potentially impact MCP-5 activity. | ||||||
Azelastine | 58581-89-8 | sc-337544 sc-337544A sc-337544B | 100 mg 500 mg 1 g | $220.00 $550.00 $700.00 | ||
Azelastine, an antihistamine, may modulate mast cell activity and indirectly influence MCP-5. | ||||||