MARCKSL1 Inhibitors
The inhibitors listed above primarily target Protein Kinase C (PKC), a key regulator of MARCKSL1. By modulating PKC activity, these compounds can indirectly influence the function of MARCKSL1, especially in regards to its role in cytoskeletal organization and cell motility. Staurosporine, Gö 6983, Bisindolylmaleimide I, Calphostin C, and Chelerythrine are inhibitors that can directly impact PKC activity, thereby potentially modulating MARCKSL1 function.
Rottlerin and Balanol, although with some considerations regarding specificity for PKC, can also influence MARCKSL1 through their effects on PKC. C1 Domain Inhibitor Peptide specifically targets the C1 domain of PKC, which is crucial for its activation and subsequent regulation of downstream targets like MARCKSL1. Selective inhibitors such as Ruboxistaurin and Sotrastaurin target specific isoforms of PKC, potentially altering MARCKSL1 regulation in specific cellular contexts. Ingenol and Bryostatin 1 are known to modulate PKC, and their effects on PKC activity could indirectly impact MARCKSL1.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Staurosporine is a broad-spectrum PKC inhibitor, which can indirectly affect MARCKSL1 function by modulating PKC activity. | ||||||
Bisindolylmaleimide I (GF 109203X) | 133052-90-1 | sc-24003A sc-24003 | 1 mg 5 mg | $103.00 $237.00 | 36 | |
Bisindolylmaleimide I is another specific PKC inhibitor, potentially impacting MARCKSL1's interaction with PKC. | ||||||
Calphostin C | 121263-19-2 | sc-3545 sc-3545A | 100 µg 1 mg | $336.00 $1642.00 | 20 | |
Calphostin C, a PKC inhibitor that acts upon light activation, could indirectly modulate MARCKSL1 activity. | ||||||
Chelerythrine chloride | 3895-92-9 | sc-3547 sc-3547A | 5 mg 25 mg | $88.00 $311.00 | 17 | |
Chelerythrine is a PKC inhibitor that could indirectly modulate the function of MARCKSL1. | ||||||
Balanol | 63590-19-2 | sc-503251 | 10 mg | $13500.00 | ||
Balanol is a potent and selective inhibitor of PKC, which may impact MARCKSL1 activity. | ||||||
LY-333,531 Hydrochloride | 169939-93-9 | sc-364215 sc-364215A | 1 mg 5 mg | $92.00 $281.00 | 6 | |
Ruboxistaurin, a selective inhibitor of PKCβ, could indirectly affect pathways involving MARCKSL1. | ||||||
Sotrastaurin | 425637-18-9 | sc-474229 sc-474229A | 5 mg 10 mg | $300.00 $540.00 | ||
Sotrastaurin is an inhibitor of several PKC isoforms, potentially influencing MARCKSL1's function. | ||||||
Ingenol | 30220-46-3 | sc-202184 sc-202184A sc-202184B sc-202184C | 1 mg 5 mg 10 mg 25 mg | $69.00 $305.00 $446.00 $1120.00 | 1 | |
Ingenol, an activator of PKC, could indirectly influence MARCKSL1 by modulating PKC activity. | ||||||
Bryostatin 1 | 83314-01-6 | sc-201407 | 10 µg | $240.00 | 9 | |
Bryostatin 1, a PKC modulator, might have indirect effects on MARCKSL1 through its action on PKC. | ||||||