Date published: 2025-10-31

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LYRM7 Activators

LYRM7, or LYR Motif Containing 7, is a protein that plays a crucial role in mitochondrial function, particularly in the assembly and maintenance of the mitochondrial respiratory chain. This protein is part of the LYR family of proteins, which are characterized by the presence of a LYR motif, a sequence that is involved in the formation and stabilization of protein complexes, especially those related to mitochondrial processes.

The primary function of LYRM7 is associated with the assembly of mitochondrial complex III, a key component of the electron transport chain. This complex is essential for the process of oxidative phosphorylation, which is the primary method by which cells generate ATP, the energy currency of the cell. LYRM7 is believed to interact with other mitochondrial proteins to facilitate the correct assembly and functioning of this complex.Defects or dysregulation in LYRM7 can have significant implications for cellular energy metabolism. Given its role in the respiratory chain, abnormalities in LYRM7 can lead to impaired mitochondrial function, which in turn can affect a wide range of cellular processes. This can manifest in various pathological conditions, particularly those related to energy metabolism and mitochondrial disorders.

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