Staurosporine and imatinib are kinase inhibitors that can modulate signal transduction pathways, affecting the activity of numerous proteins within a cell, including the presumed activities of LOC728730. PD 0332991 hydrochloride and thapsigargin can arrest cell cycle progression and disrupt calcium homeostasis, respectively, thereby influencing processes that could be critical for the function of LOC728730. Brefeldin A's inhibition of protein trafficking and 2-Deoxy-D-glucose's interference with glycolysis can alter the cellular environment in ways that may impinge upon the stability and activity of LOC728730.
MG132's impact on proteasomal degradation and cyclosporin A's inhibition of calcineurin can influence the turnover and signaling dynamics of proteins, which may include LOC728730. Z-VAD-FMK's prevention of apoptosis and lapatinib's disruption of growth factor signaling can modulate cell survival and proliferation pathways, potentially affecting LOC728730's regulatory roles. Oligomycin's inhibition of ATP synthase and curcumin's wide-ranging modulation of signaling pathways can alter the metabolic and inflammatory states of cells, respectively, creating conditions that might impact the function of LOC728730.
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