Date published: 2025-9-12

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LOC727804 Inhibitors

Triciribine and Staurosporine represent inhibitors that can interfere with kinase signaling, a fundamental mechanism of action in cellular communication and regulation. Triciribine's targeted inhibition of AKT phosphorylation, and Staurosporine's broader kinase inhibition profile, can lead to alterations in downstream signaling that may encompass the modulation of LOC727804. Celecoxib and Imatinib are representatives of inhibitors that target inflammation and specific tyrosine kinases, respectively. Celecoxib's action on COX-2 could affect inflammatory pathways, whereas Imatinib's inhibition of BCR-ABL and other kinases could alter various signaling cascades, which in turn may affect LOC727804.

Palbociclib's ability to halt cell cycle progression and Bortezomib's role in disrupting protein degradation suggest that the stability or expression of LOC727804 could be influenced by perturbations in cell cycle control or proteostasis. Sorafenib and Curcumin can impact cell growth and survival pathways, potentially altering the regulatory networks that LOC727804 is part of. Rapamycin and 1,1-Dimethylbiguanide, Hydrochloride can modulate mTOR signaling and metabolic pathways, respectively, leading to changes in protein synthesis and energy metabolism, which could indirectly affect LOC727804. Chloroquine's impact on autophagy and 2-Deoxy-D-glucose's inhibition of glycolysis offer mechanisms by which cellular stress responses and energy levels can be modified, potentially influencing the function or expression of LOC727804.

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