LOC100039633 inhibitors represent a specific category of chemical compounds meticulously designed to target and inhibit the function of the protein encoded by the gene LOC100039633. This gene is part of a group identified through comprehensive genomic studies, known for their unique expression patterns that hint at specific roles in cellular functions. While the full biological significance of the protein encoded by LOC100039633 is not entirely understood, it is hypothesized to be involved in distinct cellular processes, as indicated by genomic and proteomic data. The development of inhibitors for this protein is based on a thorough understanding of its molecular structure and the way it functions within cells. The primary aim in designing LOC100039633 inhibitors is to disrupt the functional interactions of this protein, with the goal of elucidating its role in cellular mechanisms and potentially influencing these processes. This requires the identification of critical domains or active sites within the protein that are essential for its functionality, followed by the creation of molecules that can specifically bind to these sites and effectively inhibit the protein's activity.
The process of developing LOC100039633 inhibitors is a complex and interdisciplinary endeavor, encompassing expertise in biochemistry, molecular biology, and pharmacology. Researchers engaged in this field concentrate on determining the structural details of the LOC100039633 protein. Utilizing advanced techniques, they aim to map the protein's structure, especially focusing on areas significant for its function. This structural knowledge is crucial for the targeted design of inhibitors that are both specific to their target and effective in their inhibitory action. The interaction between these inhibitors and the LOC100039633 protein is a key factor in their efficacy. The inhibitors must bind to the protein in a way that impedes its normal cellular interactions, typically leading to the formation of a complex that inhibits the protein from carrying out its typical functions. This interaction requires a highly accurate alignment of the molecular structures of the inhibitor and the protein. In addition to their binding properties, the design of LOC100039633 inhibitors also takes into account factors such as the compound's stability, solubility, and its ability to effectively reach and interact with the target site within biological systems. Researchers also work to optimize the pharmacokinetic properties of these inhibitors, ensuring they possess appropriate hydrophobic and hydrophilic properties and an optimal molecular size and shape for efficient interaction. The development of LOC100039633 inhibitors highlights the advanced level of current research in molecular targeting, emphasizing the intricacies involved in designing specific inhibitors for proteins that, while not fully characterized, may hold significant importance in biological processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor that can downregulate genes involved in cell growth and proliferation. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Inhibits eukaryotic protein synthesis by interfering with the translocation step in protein synthesis, potentially reducing overall protein levels. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Binds to DNA and prevents the transcription of mRNA by inhibiting RNA polymerase, thus reducing protein synthesis. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
A topoisomerase I inhibitor that can interfere with DNA replication and transcription, potentially leading to reduced gene expression. | ||||||
Puromycin | 53-79-2 | sc-205821 sc-205821A | 10 mg 25 mg | $163.00 $316.00 | 436 | |
Causes premature chain termination during translation by acting as an analog of aminoacyl-tRNA, which can inhibit protein synthesis. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $97.00 $254.00 | 36 | |
Inhibits peptide bond formation by binding to the 60S subunit of the eukaryotic ribosome, affecting protein synthesis. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $169.00 $299.00 | 66 | |
Inhibits N-linked glycosylation and can cause ER stress, which may downregulate protein expression. | ||||||
Chloramphenicol | 56-75-7 | sc-3594 | 25 g | $53.00 | 10 | |
Binds to bacterial ribosomes and inhibits protein synthesis, but can also affect mitochondrial protein synthesis in eukaryotic cells. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
Inhibits RNA polymerase II in eukaryotic cells, leading to a halt in mRNA synthesis and gene expression. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $95.00 $322.00 $663.00 $1438.00 | 6 | |
Inhibits bacterial RNA polymerase, and can also inhibit mitochondrial RNA polymerase, affecting gene expression in eukaryotes. | ||||||