LMO3 inhibitors belong to a distinct chemical class characterized by their ability to selectively target and modulate the activity of the LIM domain-only protein 3 (LMO3). LMO3 is a transcriptional regulator that plays a crucial role in cellular processes by participating in protein-protein interactions and influencing gene expression. The chemical entities classified as LMO3 inhibitors are designed to specifically bind to the LMO3 protein, disrupting its normal functioning or impeding its interaction with other cellular components. This targeted approach makes LMO3 inhibitors a subject of significant interest in the realm of molecular research.
LMO3 inhibitors often exhibit a specific arrangement of functional groups that facilitates their interaction with the LMO3 protein's binding site. Researchers employ various synthetic and computational methods to design molecules with optimal size, shape, and chemical properties for effective binding to the target protein. Understanding the three-dimensional structure of the LMO3 protein is crucial in guiding the rational design of these inhibitors. As researchers continue to explore the molecular intricacies of LMO3 and its role in cellular processes, the development of novel LMO3 inhibitors may contribute valuable insights into the regulatory mechanisms governing gene expression and could have potential implications for furthering our understanding of cellular biology and disease pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin can inhibit the NF-kB pathway, which LMO3 is known to activate. This inhibition can decrease the activity of LMO3. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol can suppress the activation of STAT3, a transcription factor that is activated by LMO3. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG can inhibit the JAK/STAT pathway, which is activated by LMO3. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin can affect the PI3K/AKT pathway, which is associated with LMO3. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Berberine can inhibit the MAPK pathway, which LMO3 is known to activate. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein can inhibit tyrosine kinases, which are critical for LMO3's role in cellular signaling. | ||||||
Indole-3-carbinol | 700-06-1 | sc-202662 sc-202662A sc-202662B sc-202662C sc-202662D | 1 g 5 g 100 g 250 g 1 kg | $39.00 $61.00 $146.00 $312.00 $1032.00 | 5 | |
Indole-3-Carbinol can modulate the Wnt/β-catenin pathway, which has an interplay with LMO3 functioning. | ||||||
Piperine | 94-62-2 | sc-205809 sc-205809A | 5 g 25 g | $37.00 $146.00 | 3 | |
Piperine can affect the NF-kB pathway, which is associated with LMO3. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $96.00 $160.00 $240.00 $405.00 | 26 | |
Capsaicin can activate the TRPV1 channel, leading to decreased LMO3 activity. | ||||||
Luteolin | 491-70-3 | sc-203119 sc-203119A sc-203119B sc-203119C sc-203119D | 5 mg 50 mg 500 mg 5 g 500 g | $27.00 $51.00 $101.00 $153.00 $1925.00 | 40 | |
Luteolin can affect the PI3K/AKT pathway, which is associated with LMO3. | ||||||