LCE1A Activators represent a distinct class of chemical compounds or molecules that have garnered significant interest in the field of molecular biology and cellular research. These activators are designed or discovered with the specific objective of modulating the activity of the LCE1A gene. LCE1A, or Late Cornified Envelope 1A, is a protein-coding gene found in humans. It belongs to the late cornified envelope (LCE) gene family, which encodes proteins that are important for skin barrier function and the formation of the stratum corneum, the outermost layer of the epidermis.
The study of LCE1A activators holds promise as it allows researchers to investigate the precise role of the LCE1A gene in cellular physiology and molecular mechanisms. Activation of LCE1A can provide valuable insights into its involvement in processes related to skin development, epidermal barrier function, and responses to environmental stressors. By manipulating the activity of LCE1A through these activators, scientists aim to gain a deeper understanding of the complex molecular pathways and cellular functions that rely on the gene product, thereby contributing to the broader knowledge of gene regulation and cellular behavior. Consequently, LCE1A activators serve as essential tools for researchers dedicated to unraveling the intricate molecular mechanisms that underlie cellular biology and the specific roles played by individual genes in these processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
1α,25-Dihydroxyvitamin D3 | 32222-06-3 | sc-202877B sc-202877A sc-202877C sc-202877D sc-202877 | 50 µg 1 mg 5 mg 10 mg 100 µg | $220.00 $645.00 $1000.00 $1500.00 $440.00 | 32 | |
The active form of vitamin D that may promote skin barrier formation by inducing differentiation of keratinocytes, potentially upregulating LCE1A. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
A metabolite of vitamin A that regulates keratinocyte differentiation and could stimulate LCE1A expression as part of the skin's adaptive response. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $55.00 $131.00 $203.00 $317.00 | 23 | |
Increases intracellular calcium, which is a key regulator of keratinocyte differentiation and may induce LCE1A expression. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Activates protein kinase C (PKC) signaling, leading to keratinocyte differentiation and possibly upregulating LCE1A. | ||||||
Hydrocortisone | 50-23-7 | sc-300810 | 5 g | $102.00 | 6 | |
A glucocorticoid that can influence skin cell proliferation and differentiation, potentially affecting LCE1A expression. | ||||||
Sodium dodecyl sulfate | 151-21-3 | sc-264510 sc-264510A sc-264510B sc-264510C | 25 g 100 g 500 g 1 kg | $78.00 $119.00 $419.00 $603.00 | 11 | |
A surfactant that disrupts the lipid barrier of the skin, potentially inducing LCE1A expression as a compensatory mechanism to strengthen the barrier. | ||||||