Date published: 2026-4-1

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LCE1A Activators

LCE1A Activators represent a distinct class of chemical compounds or molecules that have garnered significant interest in the field of molecular biology and cellular research. These activators are designed or discovered with the specific objective of modulating the activity of the LCE1A gene. LCE1A, or Late Cornified Envelope 1A, is a protein-coding gene found in humans. It belongs to the late cornified envelope (LCE) gene family, which encodes proteins that are important for skin barrier function and the formation of the stratum corneum, the outermost layer of the epidermis.

The study of LCE1A activators holds promise as it allows researchers to investigate the precise role of the LCE1A gene in cellular physiology and molecular mechanisms. Activation of LCE1A can provide valuable insights into its involvement in processes related to skin development, epidermal barrier function, and responses to environmental stressors. By manipulating the activity of LCE1A through these activators, scientists aim to gain a deeper understanding of the complex molecular pathways and cellular functions that rely on the gene product, thereby contributing to the broader knowledge of gene regulation and cellular behavior. Consequently, LCE1A activators serve as essential tools for researchers dedicated to unraveling the intricate molecular mechanisms that underlie cellular biology and the specific roles played by individual genes in these processes.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

1α,25-Dihydroxyvitamin D3

32222-06-3sc-202877B
sc-202877A
sc-202877C
sc-202877D
sc-202877
50 µg
1 mg
5 mg
10 mg
100 µg
$220.00
$645.00
$1000.00
$1500.00
$440.00
32
(2)

The active form of vitamin D that may promote skin barrier formation by inducing differentiation of keratinocytes, potentially upregulating LCE1A.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

A metabolite of vitamin A that regulates keratinocyte differentiation and could stimulate LCE1A expression as part of the skin's adaptive response.

A23187

52665-69-7sc-3591
sc-3591B
sc-3591A
sc-3591C
1 mg
5 mg
10 mg
25 mg
$55.00
$131.00
$203.00
$317.00
23
(1)

Increases intracellular calcium, which is a key regulator of keratinocyte differentiation and may induce LCE1A expression.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$41.00
$132.00
$214.00
$500.00
$948.00
119
(6)

Activates protein kinase C (PKC) signaling, leading to keratinocyte differentiation and possibly upregulating LCE1A.

Hydrocortisone

50-23-7sc-300810
5 g
$102.00
6
(1)

A glucocorticoid that can influence skin cell proliferation and differentiation, potentially affecting LCE1A expression.

Sodium dodecyl sulfate

151-21-3sc-264510
sc-264510A
sc-264510B
sc-264510C
25 g
100 g
500 g
1 kg
$78.00
$119.00
$419.00
$603.00
11
(1)

A surfactant that disrupts the lipid barrier of the skin, potentially inducing LCE1A expression as a compensatory mechanism to strengthen the barrier.