KRTAP19-4 Inhibitors
KRTAP19-4 Inhibitors refer to a class of chemicals that have the capacity to modulate the function or interaction of the Keratin Associated Protein 19-4 within the intricate keratin framework of hair. One of the pivotal chemical strategies for influencing KRTAP19-4 centers on targeting the disulfide bonds crucial to hair structure. Cysteamine, 2-Mercaptoethanol, and Dithiothreitol possess this capability, and their interaction with these bonds can subsequently alter the functional dynamics of KRTAP19-4.
The intricate differentiation process of keratinocytes, where KRTAP19-4 has a role, can be influenced by compounds such as SP600125, PD98059, and SB202190. These chemicals, by affecting this core cellular process, modulate the behavior and interaction of KRTAP19-4. Another realm of chemical interaction comes through substances like Ammonium Thioglycolate, primarily used in hair cosmetics. Its capacity to change hair's physical structure signifies a potential to influence KRTAP19-4. Lastly, kinase inhibitors like Ruxolitinib and Imatinib underline the interconnectedness of cellular processes.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cysteamine | 60-23-1 | sc-217991 sc-217991A sc-217991B | 5 g 25 g 50 g | $87.00 $233.00 $433.00 | 1 | |
Reduces disulfide bonds in keratins, which can affect KRTAP19-4 interaction with keratin. | ||||||
β-Mercaptoethanol | 60-24-2 | sc-202966A sc-202966 | 100 ml 250 ml | $88.00 $118.00 | 10 | |
Reduces disulfide bonds; can alter keratin structure and thus KRTAP19-4 function. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor which can disrupt keratinocyte differentiation, influencing KRTAP19-4. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
MEK inhibitor; by modulating keratinocyte differentiation, it can affect KRTAP19-4. | ||||||
SB202190 hydrochloride | 350228-36-3 | sc-222294 sc-222294A | 1 mg 5 mg | $128.00 $495.00 | 13 | |
p38 MAPK inhibitor, potentially influencing keratinocyte differentiation and KRTAP19-4 indirectly. | ||||||
Dimethyl Sulfoxide (DMSO) | 67-68-5 | sc-202581 sc-202581A sc-202581B | 100 ml 500 ml 4 L | $30.00 $115.00 $900.00 | 136 | |
A solvent that can disrupt protein-protein interactions, possibly affecting KRTAP19-4. | ||||||
Ruxolitinib | 941678-49-5 | sc-364729 sc-364729A sc-364729A-CW | 5 mg 25 mg 25 mg | $246.00 $490.00 $536.00 | 16 | |
JAK inhibitor, modulates signaling pathways in keratinocytes, potentially influencing KRTAP19-4. | ||||||
Imatinib | 152459-95-5 | sc-267106 sc-267106A sc-267106B | 10 mg 100 mg 1 g | $25.00 $117.00 $209.00 | 27 | |
Kinase inhibitor; modulates various signaling pathways in keratinocytes which can indirectly affect KRTAP19-4. | ||||||