KRCC1 inhibitors belong to a distinct chemical class of compounds known for their significant role in biochemical research. These inhibitors specifically target KRCC1, a protein that plays a crucial role in cellular processes. Within the context of cellular biology, KRCC1 is involved in various essential functions, such as DNA repair and maintenance, chromatin organization, and regulation of gene expression. By selectively inhibiting KRCC1, these compounds offer valuable insights into the intricate mechanisms that govern cellular processes and contribute to the understanding of fundamental biological pathways. Researchers have been keenly interested in exploring the activity and properties of KRCC1 inhibitors due to their potential implications in cancer research and other diseases associated with DNA damage and repair mechanisms. The ability of these inhibitors to modulate KRCC1's function provides a means to explore its precise role in DNA repair processes and the maintenance of genome stability. Consequently, they are valuable tools in the study of DNA repair pathways, helping researchers furthering our understanding of cellular responses to genotoxic stress.
Moreover, the investigation of KRCC1 inhibitors extends beyond the realm of cellular biology, as these compounds also hold promise in elucidating the intricate interactions between proteins and nucleic acids. By probing the molecular interactions involving KRCC1, scientists gain valuable insights into the complex regulatory networks that govern genetic information, shedding light on the underlying molecular mechanisms that dictate cellular responses to various environmental factors. In conclusion, KRCC1 inhibitors represent a distinct chemical class with profound significance in biochemical research and the study of cellular processes. By selectively targeting the KRCC1 protein, these compounds contribute to a deeper understanding of essential biological pathways, DNA repair mechanisms, and protein-nucleic acid interactions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
S-Trityl-L-cysteine | 2799-07-7 | sc-202799 sc-202799A | 1 g 5 g | $32.00 $66.00 | 6 | |
One of the earliest identified KRCC1 inhibitors, STLC prevents the proper function of the mitotic spindle and disrupts cell division. | ||||||
Reversine | 656820-32-5 | sc-203236 | 5 mg | $221.00 | 13 | |
An experimental compound that targets KRCC1 and inhibits its activity during mitosis. | ||||||
ZM-447439 | 331771-20-1 | sc-200696 sc-200696A | 1 mg 10 mg | $153.00 $356.00 | 15 | |
A selective inhibitor of Aurora kinase B, which indirectly affects the function of KRCC1 and other mitotic proteins. | ||||||
GSK 923295 | 1088965-37-0 | sc-490136 | 5 mg | $290.00 | ||
Another inhibitor of Aurora kinase B, which can impact KRCC1 function and disrupt mitosis. | ||||||
AZ 3146 | 1124329-14-1 | sc-361114 sc-361114A | 10 mg 50 mg | $218.00 $905.00 | 7 | |
A potent and selective inhibitor of monopolar spindle 1 (MPS1), a kinase involved in mitotic spindle assembly and checkpoint regulation. | ||||||
Hesperadin | 422513-13-1 | sc-490384 | 10 mg | $304.00 | ||
A potent and selective inhibitor of Aurora kinase B, similar to ZM447439 and GSK923295. | ||||||