KLK9 Activators
Chemical activators of KLK9, or kallikrein-related peptidase 9, are largely focused on managing the overall activity of serine proteases, the enzyme family to which KLK9 belongs. Several of these compounds, such as Benzamidine, Diisopropylfluorophosphate (DFP), AEBSF, PMSF, Leupeptin, Antipain, Chymostatin, TPCK, TLCK, and Gabexate, operate as inhibitors of serine proteases. They function by binding to and inhibiting the enzymes' active site, thereby modulating their activity. This process can indirectly influence KLK9 activity, given that KLK9 is a member of this enzyme class.
E64, on the other hand, is a potent inhibitor of cysteine proteases, and its inhibitory function can indirectly alter the overall function and balance of protease activity, including that of serine proteases like KLK9. Collectively, these compounds provide an array of chemical activators that can potentially influence the activity of KLK9 through varied mechanisms.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Benzamidine | 618-39-3 | sc-233933 | 10 g | $286.00 | 1 | |
Benzamidine is a competitive inhibitor of serine proteases that can bind to the active site of these enzymes and displace the substrate, potentially modulating KLK9 activity. | ||||||
AEBSF hydrochloride | 30827-99-7 | sc-202041 sc-202041A sc-202041B sc-202041C sc-202041D sc-202041E | 50 mg 100 mg 5 g 10 g 25 g 100 g | $50.00 $120.00 $420.00 $834.00 $1836.00 $4896.00 | 33 | |
AEBSF is a serine protease inhibitor. It inhibits by forming a covalent bond with the serine in the active site of the enzyme, which can indirectly influence KLK9 activity. | ||||||
Leupeptin hemisulfate | 103476-89-7 | sc-295358 sc-295358A sc-295358D sc-295358E sc-295358B sc-295358C | 5 mg 25 mg 50 mg 100 mg 500 mg 10 mg | $72.00 $145.00 $265.00 $489.00 $1399.00 $99.00 | 19 | |
Leupeptin is a known inhibitor of serine proteases. By inhibiting these enzymes, it can indirectly modulate KLK9 activity. | ||||||
Chymostatin | 9076-44-2 | sc-202541 sc-202541A sc-202541B sc-202541C sc-202541D | 5 mg 10 mg 25 mg 50 mg 100 mg | $153.00 $255.00 $627.00 $1163.00 $2225.00 | 3 | |
Chymostatin is a protease inhibitor that inhibits serine and cysteine proteases, potentially affecting KLK9 activity. | ||||||
E-64 | 66701-25-5 | sc-201276 sc-201276A sc-201276B | 5 mg 25 mg 250 mg | $275.00 $928.00 $1543.00 | 14 | |
E64 is a potent inhibitor of cysteine proteases. By inhibiting these enzymes, E64 can indirectly alter the function of serine proteases like KLK9. | ||||||
TPCK | 402-71-1 | sc-201297 | 1 g | $178.00 | 2 | |
TPCK selectively inhibits chymotrypsin-like serine proteases, potentially influencing KLK9. | ||||||
Gabexate mesylate | 56974-61-9 | sc-215066 | 5 mg | $100.00 | ||
Gabexate is a serine protease inhibitor. It inhibits by forming a covalent bond with the serine in the active site of the enzyme, potentially influencing KLK9 activity. | ||||||