KLHL31 Activators
Kelch Like Family Member 31 (KLHL31) is a protein encoded by the KLHL31 gene in humans. This protein is part of the larger kelch-like (KLHL) protein family, which are characterized by a conserved kelch repeat domain.Kelch-like proteins typically function as substrate-specific adaptors for Cullin 3 (CUL3)-based ubiquitin ligases. These enzymes play a key role in the ubiquitin-proteasome system, which is responsible for protein degradation in cells. By recognizing and binding to specific target proteins, KLHL proteins help facilitate their ubiquitination and subsequent degradation.
In zebrafish models, KLHL31 has been implicated in the regulation of muscle development, while in humans, dysregulation of KLHL31 has been associated with congenital muscular dystrophy. In summary, KLHL31 is a member of the kelch-like protein family, potentially involved in protein degradation pathways through its interaction with Cullin 3-based ubiquitin ligases. Predominantly expressed in skeletal muscle, it is thought to play a role in muscle development or function.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium influences the Wnt signaling pathway, which might intersect with pathways involving KLHL31, thus potentially affecting its activity. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin, by increasing cAMP levels, could indirectly influence signaling pathways that intersect with KLHL31 functions. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
As a histone deacetylase inhibitor, Trichostatin A can alter gene expression patterns, potentially impacting KLHL31 expression. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin inhibits mTOR, a key regulator in cell growth and proliferation, which might have downstream effects on KLHL31 activity. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA activates protein kinase C (PKC), potentially influencing cellular processes where KLHL31 is involved. | ||||||
L-Tryptophan | 73-22-3 | sc-280888 sc-280888A sc-280888B | 100 g 1 kg 5 kg | $129.00 $364.00 $1795.00 | ||
Activators of the Wnt pathway may indirectly modulate the function or expression of KLHL31. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium butyrate, another histone deacetylase inhibitor, may influence gene expression related to KLHL31. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
This selective inhibitor of ALK5 might influence signaling pathways relevant to KLHL31 activity. | ||||||