Date published: 2026-3-26

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KLHL20 Activators

KLHL20 activators constitute a specialized class of chemical compounds that have garnered attention in the field of molecular biology and genetics. These compounds are designed to modulate the activity of KLHL20, a protein-coding gene known to be involved in various cellular processes. KLHL20, which stands for Kelch-Like Family Member 20, is characterized by its Kelch repeat domains, which are involved in protein-protein interactions and substrate recognition. KLHL20 activators function by targeting specific regulatory elements within the KLHL20 gene, often located in promoter or enhancer regions, with the primary aim of enhancing its transcription and subsequent translation into functional protein products.

The mechanisms through which KLHL20 activators exert their effects may vary, but their core objective is to act as molecular switches, amplifying the activity of KLHL20. Researchers are continually exploring the potential applications and implications of KLHL20 activation, with the goal of deepening our understanding of how this gene contributes to cellular processes, particularly those related to protein-protein interactions and substrate recognition. This class of compounds holds promise for advancing our knowledge of gene regulation, particularly within the context of Kelch repeat-containing proteins and their roles in various biological processes, offering insights into the intricate mechanisms that govern the function of KLHL20 in different cellular contexts. KLHL20 activators serve as valuable tools in ongoing investigations within molecular biology, providing opportunities to elucidate the complex roles that KLHL20 plays in cellular processes and its significance in protein-protein interactions.

SEE ALSO...

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Metformin

657-24-9sc-507370
10 mg
$79.00
2
(0)

As an AMPK activator, Metformin could alter cellular energy status, potentially affecting signaling pathways and gene expression, including KLHL20.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol activates SIRT1, a NAD+-dependent deacetylase, potentially influencing energy metabolism and stress responses, including KLHL20 expression.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin modulates various signaling pathways (e.g., NF-κB, Wnt/β-catenin), potentially affecting the expression of genes like KLHL20.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$31.00
$47.00
$84.00
$222.00
19
(3)

As an HDAC inhibitor, Sodium Butyrate can alter chromatin structure and gene expression differently, potentially affecting KLHL20.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Lithium can inhibit GSK-3β, potentially affecting Wnt/β-catenin signaling and the expression of related genes, including KLHL20.

Salicylic acid

69-72-7sc-203374
sc-203374A
sc-203374B
100 g
500 g
1 kg
$47.00
$94.00
$119.00
3
(1)

Salicylate can inhibit NF-κB, potentially modulating inflammatory responses and influencing the expression of genes like KLHL20.

Pioglitazone

111025-46-8sc-202289
sc-202289A
1 mg
5 mg
$55.00
$125.00
13
(1)

As a PPARγ agonist, Pioglitazone can influence lipid metabolism and insulin sensitivity, potentially affecting gene expression, including KLHL20.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$153.00
$292.00
$489.00
$1325.00
$8465.00
$933.00
22
(1)

Sulforaphane activates Nrf2, a key regulator of antioxidant response, potentially influencing the expression of detoxifying genes, including KLHL20.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

Quercetin, a flavonoid, can modulate various signaling pathways and potentially influence gene expression, including KLHL20.

Arsenic(III) oxide

1327-53-3sc-210837
sc-210837A
250 g
1 kg
$89.00
$228.00
(0)

Used in treating acute promyelocytic leukemia, Arsenic Trioxide can induce oxidative stress and affect gene expression, potentially including KLHL20.