Date published: 2026-5-30

1-800-457-3801

SCBT Portrait Logo
Seach Input

KIR2.4 Inhibitors

KIR2.4 inhibitors comprise a set of diverse compounds that exert their effects on KIR2.4 indirectly by targeting various cellular pathways and molecular processes. Baicalein, for instance, inhibits the NF-κB pathway, interfering with the transcriptional regulation of genes involved in KIR2.4 expression. Similarly, SB-203580 modulates KIR2.4 by inhibiting p38 MAPK signaling, altering downstream pathways influencing its expression and function. LY294002, a PI3K inhibitor, disrupts the PI3K/AKT pathway, indirectly impacting KIR2.4 by altering cellular processes related to its regulation. Dasatinib, through Src family kinase inhibition, influences KIR2.4 by disrupting downstream signaling pathways. PD98059 modulates KIR2.4 indirectly by inhibiting the MAPK/ERK pathway, affecting its expression and function. Wortmannin, another PI3K inhibitor, and SP600125, a JNK inhibitor, both indirectly affect KIR2.4 by disrupting the PI3K/AKT and JNK pathways, respectively. Celecoxib, a COX-2 inhibitor, modulates KIR2.4 by altering downstream signaling cascades. U0126 influences KIR2.4 by inhibiting the MAPK/ERK pathway, impacting its expression and function. AG490 and Tofacitinib, JAK inhibitors, indirectly affect KIR2.4 by disrupting the JAK2/STAT pathway, altering downstream signaling cascades related to KIR2.4 regulation. BAY 11-7082 inhibits NF-κB signaling, influencing the transcription of genes involved in KIR2.4 expression and function. This class of compounds demonstrates the intricate web of cellular interactions that can be harnessed to indirectly modulate KIR2.4, highlighting their potential as tools for further investigation into the intricacies of cellular signaling pathways.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Baicalein

491-67-8sc-200494
sc-200494A
sc-200494B
sc-200494C
10 mg
100 mg
500 mg
1 g
$32.00
$42.00
$162.00
$292.00
12
(1)

Affects KIR2.4 indirectly by inhibiting the NF-κB pathway. Baicalein interferes with the phosphorylation and degradation of IκBα, reducing NF-κB activation. This modulation of the NF-κB pathway can influence the transcription of genes involved in KIR2.4 expression and function.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$90.00
$349.00
284
(5)

Indirectly modulates KIR2.4 by inhibiting p38 MAPK signaling. SB-203580 disrupts the phosphorylation of p38 MAPK, affecting downstream signaling pathways that influence the expression and function of KIR2.4.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

A PI3K inhibitor influencing KIR2.4 indirectly. LY294002 disrupts the PI3K/AKT pathway, altering downstream signaling cascades that impact KIR2.4 expression and function. The modulation of this pathway can influence the cellular processes related to KIR2.4 regulation.

Dasatinib

302962-49-8sc-358114
sc-358114A
25 mg
1 g
$70.00
$145.00
51
(1)

Affects KIR2.4 indirectly through Src family kinase inhibition. Dasatinib disrupts downstream signaling, altering pathways involved in KIR2.4 expression and function. The modulation of these pathways can impact cellular processes related to KIR2.4 regulation.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$40.00
$92.00
212
(2)

Modulates KIR2.4 indirectly by inhibiting the MAPK/ERK pathway. PD98059 disrupts the phosphorylation of MEK1/2, affecting downstream signaling cascades that influence KIR2.4 expression and function.

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$67.00
$223.00
$425.00
97
(3)

Influences KIR2.4 indirectly through PI3K inhibition. Wortmannin disrupts the PI3K/AKT pathway, altering downstream signaling cascades that impact KIR2.4 expression and function. The modulation of this pathway can influence cellular processes related to KIR2.4 regulation.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

Indirectly modulates KIR2.4 by inhibiting the JNK pathway. SP600125 disrupts JNK signaling, affecting downstream pathways that influence KIR2.4 expression and function. The modulation of these pathways can impact cellular processes related to KIR2.4 regulation.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$64.00
$246.00
136
(2)

Indirectly influences KIR2.4 by inhibiting the MAPK/ERK pathway. U0126 disrupts the phosphorylation of MEK1/2, affecting downstream signaling cascades that influence KIR2.4 expression and function.

AG-490

133550-30-8sc-202046C
sc-202046A
sc-202046B
sc-202046
5 mg
50 mg
25 mg
10 mg
$84.00
$329.00
$223.00
$87.00
35
(1)

JAK2 inhibitor indirectly affecting KIR2.4. AG490 disrupts the JAK2/STAT pathway, altering downstream signaling cascades that influence KIR2.4 expression and function. The modulation of this pathway can influence cellular processes related to KIR2.4 regulation.

BAY 11-7082

19542-67-7sc-200615B
sc-200615
sc-200615A
5 mg
10 mg
50 mg
$62.00
$85.00
$356.00
155
(1)

Modulates KIR2.4 indirectly by inhibiting NF-κB signaling. BAY 11-7082 interferes with the phosphorylation and degradation of IκBα, reducing NF-κB activation. This modulation of the NF-κB pathway can influence the transcription of genes involved in KIR2.4 expression and function.