KIAA1609 inhibitors constitute a class of chemical compounds designed to selectively target and modulate the activity of the KIAA1609 protein. KIAA1609, also known as CEP131 (Centrosomal Protein 131), is a protein that plays a pivotal role in cellular processes related to centrosome function and microtubule organization. Centrosomes are critical organelles within eukaryotic cells that serve as the primary microtubule-organizing centers, orchestrating various cellular processes such as cell division, intracellular transport, and ciliary assembly. KIAA1609 inhibitors are essential tools in cell biology and molecular research, enabling scientists to investigate the functional significance of KIAA1609 within these complex cellular pathways.
Researchers employ KIAA1609 inhibitors to elucidate the precise mechanisms by which KIAA1609 contributes to centrosome biology and microtubule dynamics. By selectively inhibiting KIAA1609, scientists can explore its interactions with other centrosomal proteins and its role in processes such as centrosome duplication, spindle formation, and ciliogenesis. This research aids in unraveling the intricacies of how centrosomes orchestrate various cellular events and how defects in these processes can lead to cellular dysfunction and disease. Additionally, the study of KIAA1609 inhibitors has broader implications for understanding the fundamental principles of cell biology, as centrosomes and microtubules are essential components of cellular architecture and function, impacting various cellular processes beyond centrosome-related functions. In summary, KIAA1609 inhibitors serve as indispensable tools for advancing our understanding of centrosome biology and microtubule organization, contributing to the broader field of cell biology research.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Torin 1 | 1222998-36-8 | sc-396760 | 10 mg | $240.00 | 7 | |
Torin 1 is a potent and selective mTOR inhibitor that can inhibit both mTORC1 and mTORC2, possibly affecting EAK-7 associated pathways. | ||||||
PP242 | 1092351-67-1 | sc-301606A sc-301606 | 1 mg 5 mg | $56.00 $169.00 | 8 | |
PP242 is an ATP-competitive inhibitor of mTOR that has a role in inhibiting both mTORC1 and mTORC2, potentially influencing EAK-7. | ||||||
AZD8055 | 1009298-09-2 | sc-364424 sc-364424A | 10 mg 50 mg | $160.00 $345.00 | 12 | |
AZD8055 is a selective inhibitor of mTOR kinase activity, affecting both mTORC1 and mTORC2, which could impact EAK-7 activity. | ||||||
PI-103 | 371935-74-9 | sc-203193 sc-203193A | 1 mg 5 mg | $32.00 $128.00 | 3 | |
PI-103 is a dual PI3K and mTOR inhibitor and could therefore modulate EAK-7 activity by impacting mTOR pathway signaling. | ||||||
Everolimus | 159351-69-6 | sc-218452 sc-218452A | 5 mg 50 mg | $128.00 $638.00 | 7 | |
Everolimus is a derivative of rapamycin and inhibits mTORC1; it could potentially alter EAK-7 function through mTOR modulation. | ||||||
WYE-354 | 1062169-56-5 | sc-364652 sc-364652A | 10 mg 50 mg | $286.00 $1200.00 | ||
WYE-354 is an inhibitor of mTOR that could potentially modulate EAK-7 by altering mTOR signaling. | ||||||
KU 0063794 | 938440-64-3 | sc-361219 | 10 mg | $209.00 | ||
Ku-0063794 is a selective mTOR inhibitor that may indirectly influence EAK-7 activity via mTOR pathway inhibition. | ||||||
Palomid 529 | 914913-88-5 | sc-364563 sc-364563A | 10 mg 50 mg | $300.00 $1000.00 | ||
Palomid 529 (P529) is a dual TORC1/TORC2 inhibitor, which could affect EAK-7 function by modulating downstream mTOR signaling. | ||||||
INK 128 | 1224844-38-5 | sc-364511 sc-364511A | 5 mg 50 mg | $315.00 $1799.00 | ||
Sapanisertib is a selective mTOR inhibitor, which may have an impact on EAK-7 through the mTOR pathway. | ||||||
OSI-027 | 936890-98-1 | sc-364557 sc-364557A | 10 mg 50 mg | $428.00 $1163.00 | 1 | |
OSI-027 is a selective ATP-competitive mTOR inhibitor, potentially affecting mTOR pathway-related proteins like EAK-7. | ||||||