KIAA12117/1/2014C530008M17Rik Activators
A1BG, encoding the alpha-1-B glycoprotein, presents an intriguing enigma in the landscape of plasma glycoproteins, as its specific function remains elusive. The protein exhibits sequence similarities to the variable regions of certain immunoglobulin supergene family members, hinting at a potential association with immune-related processes. Despite this, the exact role and biological significance of A1BG remain undefined. It stands as a mysterious entity in cellular biology, awaiting comprehensive elucidation.
The activation mechanisms of A1BG add another layer of complexity to its enigmatic nature. While direct activators are yet to be identified, a range of chemicals indirectly modulate A1BG. These chemicals act through diverse signaling pathways and cellular processes, suggesting an intricate network that influences the unknown function of A1BG. The proposed indirect activation pathways involve diverse mechanisms such as phosphatase inhibition, kinase signaling modulation, chromatin structure alterations, and more. The complexity and interconnectedness of these pathways underscore the sophisticated regulatory landscape governing A1BG. The absence of direct activators underscores the need for further exploration into the functional intricacies of A1BG, encouraging continued research to unravel the mystery surrounding its activation and cellular role. The identification of these chemicals and their impact on A1BG activation offers a starting point for future investigations, prompting deeper inquiries into the broader context of plasma glycoproteins and their contributions to cellular homeostasis.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic Acid influences the RA signaling pathway, potentially activating A1BG indirectly. By activating RAR/RXR receptors, it may lead to altered gene expression or post-translational modifications that impact A1BG function in an unknown cellular context. | ||||||
Calyculin A | 101932-71-2 | sc-24000 sc-24000A | 10 µg 100 µg | $163.00 $800.00 | 59 | |
Calyculin A, a protein phosphatase inhibitor, indirectly activates A1BG. By inhibiting PP1 and PP2A, Calyculin A disrupts the phosphatase balance, potentially favoring A1BG phosphorylation or altering its interaction with other cellular components, affecting its unknown function. | ||||||
Hesperidin | 520-26-3 | sc-205711 sc-205711A | 25 g 100 g | $82.00 $204.00 | 5 | |
Hesperidin, a flavonoid, modulates cellular processes that indirectly impact A1BG. It is proposed to affect specific pathways, potentially influencing A1BG through altered gene expression or post-translational modifications related to its unknown function. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein, a tyrosine kinase inhibitor, indirectly affects A1BG. By inhibiting tyrosine kinases, it may impact downstream signaling cascades, potentially modulating gene expression or post-translational modifications associated with the unknown function of A1BG. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Trichostatin A, a histone deacetylase inhibitor, indirectly influences A1BG through epigenetic modifications. By inhibiting HDACs, it may alter chromatin structure, affecting gene expression associated with A1BG's unknown function. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA, a PKC activator, indirectly influences A1BG through PKC-mediated signaling. Activated PKC may modulate downstream pathways, impacting gene expression or post-translational modifications associated with the unknown function of A1BG. The proposed indirect activation pathway suggests a link between PKC signaling and the intricate regulation of A1BG. | ||||||
8-CPT-cAMP | 93882-12-3 | sc-201569 sc-201569A | 20 mg 100 mg | $87.00 $316.00 | 19 | |
8-CPT-cAMP, a cAMP analog, indirectly activates A1BG through elevated intracellular cAMP levels. This influences downstream targets, potentially impacting gene expression or post-translational modifications associated with the unknown function of A1BG. The proposed indirect activation pathway suggests a link between cAMP-mediated signaling and the intricate regulation of A1BG. | ||||||