KCTD16 Inhibitors
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
This alkaloid acts as a potent inhibitor of protein kinases. It reduces the phosphorylation levels of proteins, thereby affecting multiple signaling cascades that rely on phosphorylation for activation. This impacts the protein-protein interactions involving KCTD16, leading to its inhibition. | ||||||
Chelerythrine | 34316-15-9 | sc-507380 | 100 mg | $540.00 | ||
A benzo[c]phenanthridine alkaloid that serves as a potent inhibitor of protein kinase C (PKC). By inhibiting PKC, it alters the downstream signaling involving phosphorylation and dephosphorylation, which is crucial for KCTD16's modulation of ion channels. | ||||||
Gö 6983 | 133053-19-7 | sc-203432 sc-203432A sc-203432B | 1 mg 5 mg 10 mg | $105.00 $299.00 $474.00 | 15 | |
A pan-PKC inhibitor that disrupts PKC-mediated signal transduction pathways. As PKC influences various cellular functions, its inhibition affects the signaling pathways that modulate the activity of KCTD16, particularly those regulating ion channel assembly and function. | ||||||
Bisindolylmaleimide I (GF 109203X) | 133052-90-1 | sc-24003A sc-24003 | 1 mg 5 mg | $105.00 $242.00 | 36 | |
This compound is a specific inhibitor of PKC. Its action reduces the activity of PKC-dependent signaling mechanisms, which indirectly leads to the inhibition of KCTD16 by preventing the proper regulation of associated potassium channels. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
As a diester of phorbol, this compound activates PKC. However, chronic application of PMA leads to PKC downregulation, which would attenuate the signaling pathways that KCTD16 is involved with, particularly in the assembly and regulation of ion channels. | ||||||
Calphostin C | 121263-19-2 | sc-3545 sc-3545A | 100 µg 1 mg | $343.00 $1642.00 | 20 | |
A specific inhibitor of PKC, Calphostin C binds to the regulatory domain of the enzyme. This binding inhibits phosphorylation events that KCTD16 may modulate or be affected by, specifically in the context of ion channel regulation. | ||||||
Ro 31-8220 | 138489-18-6 | sc-200619 sc-200619A | 1 mg 5 mg | $92.00 $245.00 | 17 | |
An inhibitor of PKC, this compound suppresses the phosphorylation-dependent signaling pathways that KCTD16 is involved in, notably affecting the modulation of ion channel complexes. | ||||||
H-89 dihydrochloride | 130964-39-5 | sc-3537 sc-3537A | 1 mg 10 mg | $94.00 $186.00 | 71 | |
This compound is an inhibitor of protein kinase A (PKA). By inhibiting PKA, it disrupts cAMP-dependent signaling pathways, which can indirectly lead to the inhibition of KCTD16 by affecting the regulation of associated ion channels. | ||||||
KT 5720 | 108068-98-0 | sc-3538 sc-3538A sc-3538B | 50 µg 100 µg 500 µg | $138.00 $220.00 $972.00 | 47 | |
An inhibitor of PKA. The inhibition of PKA by KT 5720 would lead to altered cAMP-mediated signaling processes, which are critical for the regulation of numerous proteins including KCTD16, specifically in the context of channel regulation. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
An isoflavone that acts as a tyrosine kinase inhibitor. It impairs the phosphorylation of tyrosine residues on proteins, disrupting the signaling pathways that KCTD16 could be regulating or be affected by, particularly those involving ion channel function. | ||||||