Date published: 2026-4-24

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KCNQ3 Activators

Santa Cruz Biotechnology now offers a broad range of KCNQ3 Activators for use in various applications. KCNQ3 activators are crucial in the study of ion channel modulation, particularly within the context of voltage-gated potassium channels. These channels play an essential role in controlling the electrical excitability of neurons and muscle cells by regulating potassium ion flow across cell membranes. By activating KCNQ3 channels, researchers can explore the underlying mechanisms of cellular excitability, investigate the biophysical properties of ion channels, and study the effects of these activators on cellular signaling pathways. KCNQ3 activators are invaluable tools in neuroscience, where they are used to dissect the contributions of different ion channel subtypes to neuronal function and to understand their role in maintaining the resting membrane potential and shaping action potentials. Additionally, these activators provide insights into the modulation of channel activity under physiological and pathophysiological conditions, making them indispensable for research in cellular physiology and biochemistry. View detailed information on our available KCNQ3 Activators by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

ICA 069673

582323-16-8sc-362745
sc-362745A
10 mg
50 mg
$159.00
$645.00
(0)

ICA 069673 serves as a selective modulator of KCNQ3 channels, demonstrating distinct binding affinities that promote channel resilience. Its molecular interactions are characterized by a combination of hydrogen bonding and hydrophobic interactions, which significantly impact the channel's structural integrity. The compound exhibits unique reaction kinetics, modifying the voltage-dependence of activation and enhancing ion flow regulation, thereby allowing for targeted modulation of cellular excitability.

Zinc

7440-66-6sc-213177
100 g
$48.00
(0)

Zinc Pyrithione modulates potassium channels by increasing the sensitivity of voltage-gated potassium channels like KCNQ3 to the voltage, thereby enhancing their activity and promoting the activation of KCNQ3.

SKF-89976A

85375-15-1sc-253567
10 mg
$80.00
(0)

ICA-27243 is a potent and selective activator of KCNQ2/3 channels that directly enhances the activity of the KCNQ3 subunit by stabilizing the open state of the channel, thus potentiating its conductance properties.

Etoricoxib

202409-33-4sc-218446
10 mg
$36.00
3
(1)

BMS-204352 is a Maxi-K channel opener that can also enhance KCNQ3 channel activity by increasing the open probability of the channel, thus indirectly leading to increased potassium ion efflux.

Ro 31-8220

138489-18-6sc-200619
sc-200619A
1 mg
5 mg
$92.00
$245.00
17
(1)

1-EBIO is an activator of calcium-activated potassium channels (SK and IK channels), and it can indirectly enhance KCNQ3 function by modulating cellular excitability and the overall ionic environment in which KCNQ3 operates.