Date published: 2026-5-16

1-800-457-3801

SCBT Portrait Logo
Seach Input

JWA Inhibitors

JWA inhibitors constitute a specialized category of chemical compounds that have gained prominence in the field of molecular biology and cellular response to environmental stressors. JWA, also known as ARL6IP5 or Adenylate Kinase Domain-Containing Protein 3, is a protein involved in various cellular processes, including DNA repair, cell cycle regulation, and cellular adaptation to genotoxic stress. The term JWA inhibitors refers to a group of molecules meticulously designed to selectively target and modulate the activity of JWA. These inhibitors serve as invaluable tools in laboratory investigations, enabling researchers to explore the intricate molecular functions and cellular processes associated with JWA.

JWA inhibitors typically function by interfering with the molecular interactions or enzymatic activities of JWA, thereby affecting its role in DNA damage repair and cellular stress responses. This interference can lead to alterations in cellular responses to genotoxic stressors, potentially influencing DNA repair efficiency and cell fate decisions following exposure to environmental insults. Researchers employ JWA inhibitors to gain insights into the physiological roles and molecular interactions of JWA within cells, aiming to advance our understanding of the fundamental mechanisms involved in cellular adaptation to genotoxic stress, genomic stability, and the maintenance of cell homeostasis. Through the study of JWA inhibitors, scientists seek to unravel the complexities of cellular stress responses, DNA damage repair pathways, and the broader field of molecular and cellular biology, contributing to our knowledge of how cells protect their genetic material and ensure proper functioning in challenging environments.

SEE ALSO...

Items 1 to 10 of 12 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Rifampicin

13292-46-1sc-200910
sc-200910A
sc-200910B
sc-200910C
1 g
5 g
100 g
250 g
$97.00
$328.00
$676.00
$1467.00
6
(1)

Rifampicin can inhibit DNA-dependent RNA polymerase, potentially decreasing the transcription of various genes, including JWA.

Chloroquine

54-05-7sc-507304
250 mg
$69.00
2
(0)

Chloroquine affects lysosomal function and autophagy, which might incidentally downregulate JWA expression through cellular stress pathways.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$31.00
$47.00
$84.00
$222.00
19
(3)

Sodium Butyrate is a histone deacetylase inhibitor that can alter gene expression and may reduce JWA expression as part of a broader effect on transcription.

Salubrinal

405060-95-9sc-202332
sc-202332A
1 mg
5 mg
$34.00
$104.00
87
(2)

Salubrinal inhibits dephosphorylation of eIF2α, affecting protein synthesis and potentially decreasing JWA expression under stress.

Tunicamycin

11089-65-9sc-3506A
sc-3506
5 mg
10 mg
$172.00
$305.00
66
(3)

Tunicamycin inhibits N-linked glycosylation, causing ER stress and potentially downregulating JWA as part of the unfolded protein response.

Thapsigargin

67526-95-8sc-24017
sc-24017A
1 mg
5 mg
$136.00
$446.00
114
(2)

Thapsigargin disrupts calcium homeostasis in the ER, which can lead to cellular stress and potentially reduce JWA expression.

2-Deoxy-D-glucose

154-17-6sc-202010
sc-202010A
1 g
5 g
$70.00
$215.00
26
(2)

2-Deoxy-D-glucose inhibits glycolysis and can induce metabolic stress, potentially impacting JWA expression.

Brefeldin A

20350-15-6sc-200861C
sc-200861
sc-200861A
sc-200861B
1 mg
5 mg
25 mg
100 mg
$31.00
$53.00
$124.00
$374.00
25
(3)

Brefeldin A disrupts ER to Golgi transport, affecting protein trafficking and potentially influencing JWA expression.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$41.00
$84.00
$275.00
127
(6)

Cycloheximide inhibits eukaryotic protein synthesis, which could lead to a decrease in JWA protein levels as a secondary effect.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$74.00
$243.00
$731.00
$2572.00
$21848.00
53
(3)

Actinomycin D intercalates into DNA, inhibiting RNA synthesis broadly and could decrease the expression of JWA among other genes.