IFITM7 Inhibitors
IFITM7 inhibitors constitute a class of chemical compounds specifically designed to target and interfere with the activity of the IFITM7 gene or its encoded protein product. IFITM7, or Interferon-Induced Transmembrane Protein 7, is a member of the IFITM family of proteins, which are recognized for their roles in innate immunity and antiviral defense mechanisms. These inhibitors are developed to modulate the function of IFITM7, which may participate in various cellular processes related to immune responses and antiviral defense.
The primary mechanism of action for IFITM7 inhibitors typically involves their interaction with the IFITM7 protein or its associated molecules, leading to the disruption of its normal function. By inhibiting IFITM7, these compounds have the potential to influence cellular processes related to antiviral defense and immune responses. Researchers studying IFITM7 inhibitors aim to uncover the specific roles of IFITM7 in the context of viral infections and immune system modulation. These inhibitors serve as valuable tools for advancing our understanding of the intricate mechanisms involved in host defense against viruses. In this context, they contribute to the broader field of immunology and antiviral research, shedding light on the molecular and cellular processes that underlie our innate immune responses to viral pathogens.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ruxolitinib | 941678-49-5 | sc-364729 sc-364729A sc-364729A-CW | 5 mg 25 mg 25 mg | $246.00 $490.00 $536.00 | 16 | |
Another JAK inhibitor that could impede JAK-STAT signaling, potentially downregulating ISG expression including IFITM proteins. | ||||||
Sorafenib | 284461-73-0 | sc-220125 sc-220125A sc-220125B | 5 mg 50 mg 500 mg | $56.00 $260.00 $416.00 | 129 | |
Kinase inhibitor that might indirectly lower ISG expression through inhibition of various intracellular signaling pathways. | ||||||
Sunitinib, Free Base | 557795-19-4 | sc-396319 sc-396319A | 500 mg 5 g | $150.00 $920.00 | 5 | |
Multi-targeted receptor tyrosine kinase inhibitor that may affect several signaling pathways and could attenuate ISG expression. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
PI3K inhibitor that could influence several downstream signaling pathways, potentially affecting the expression of IFITM proteins. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inhibitor of c-Jun N-terminal kinase (JNK), which might modulate transcription factors involved in ISG expression. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
Inhibitor of p38 MAPK, which could theoretically reduce the expression of some ISGs by altering the MAPK signaling pathway. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
MEK inhibitor that might impact the ERK/MAPK signaling pathway, possibly affecting ISG expression. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $61.00 $83.00 $349.00 | 155 | |
NF-κB inhibitor that may reduce ISG expression by inhibiting NF-κB, a transcription factor involved in the regulation of immune responses. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Another PI3K inhibitor with potential effects on various signaling pathways, which might influence ISG expression. | ||||||
AG-490 | 133550-30-8 | sc-202046C sc-202046A sc-202046B sc-202046 | 5 mg 50 mg 25 mg 10 mg | $82.00 $323.00 $219.00 $85.00 | 35 | |
JAK2 inhibitor that potentially affects JAK-STAT signaling, potentially downregulating ISG expression. | ||||||