HIV-1 Integrase Inhibitors
Santa Cruz Biotechnology now offers a broad range of HIV-1 Integrase Inhibitors. HIV-1 Integrase is a viral protein that catalyzes the first two steps of the three-step DNA integration process and belongs to the superfamily of polynucleotidyl transferases. The integration of HIV-1 DNA into the host chromosome is achieved by the integrase protein performing a series of DNA cleaving and ligation reactions. HIV-1 Integrase Inhibitors offered by Santa Cruz inhibit HIV-1 Integrase and, in some cases, other retrovirus and immune system related proteins. View detailed HIV-1 Integrase Inhibitor specifications, including HIV-1 Integrase Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.
Items 11 to 15 of 15 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
His-Cys-Lys-Phe-Trp-Trp | 172546-75-7 | sc-364506 | 5 mg | $212.00 | ||
His-Cys-Lys-Phe-Trp-Trp exhibits intriguing properties as an HIV-1 integrase, characterized by its ability to facilitate the integration of viral DNA into host genomes. This peptide's unique sequence allows for specific interactions with the integrase enzyme, enhancing its catalytic efficiency. The presence of aromatic residues contributes to hydrophobic interactions, stabilizing the enzyme-substrate complex. Additionally, its structural conformation may influence the kinetics of the integration process, impacting the overall viral lifecycle. | ||||||
MK-2048 | 869901-69-9 | sc-364535 sc-364535A | 5 mg 10 mg | $405.00 $555.00 | ||
MK-2048 functions as an HIV-1 integrase through its selective binding to the integrase enzyme, disrupting the integration of viral DNA into host cells. Its unique structural features promote specific electrostatic interactions, enhancing binding affinity. The compound's conformational flexibility allows it to adapt to various enzyme states, potentially altering reaction kinetics. Furthermore, its hydrophilic and hydrophobic regions facilitate critical molecular interactions, influencing the overall dynamics of the integration mechanism. | ||||||
Epiequisetin | 255377-45-8 | sc-391529 | 1 mg | $315.00 | ||
Epiequisetin acts as an HIV-1 integrase by engaging in precise molecular interactions that stabilize the enzyme-substrate complex. Its unique binding profile is characterized by a combination of hydrogen bonding and hydrophobic interactions, which modulate the enzyme's activity. The compound exhibits a distinct ability to alter the conformational landscape of integrase, impacting the efficiency of viral DNA integration. Additionally, its specific steric properties influence the reaction pathway, potentially affecting the overall kinetics of the integration process. | ||||||
Funalenone | 259728-61-5 | sc-364493 sc-364493A | 250 µg 1 mg | $60.00 $225.00 | ||
Funalenone functions as an HIV-1 integrase through its distinctive ability to form covalent interactions with key amino acid residues within the enzyme's active site. This compound exhibits a unique electronic configuration that enhances its reactivity, facilitating the formation of stable intermediates during the integration process. Its structural features allow for selective binding, which can modulate the enzyme's conformational dynamics, ultimately influencing the integration efficiency and reaction kinetics. | ||||||
BMS-707035 | 729607-74-3 | sc-364442 sc-364442A | 5 mg 200 mg | $250.00 $3749.00 | ||
BMS-707035 acts as an HIV-1 integrase by engaging in specific non-covalent interactions with the enzyme's active site, particularly through hydrogen bonding and hydrophobic contacts. Its unique stereochemistry promotes a favorable orientation for binding, enhancing its affinity for the integrase. This compound also influences the enzyme's allosteric sites, potentially altering its conformational states and impacting the overall catalytic mechanism and efficiency of the integration reaction. | ||||||