Heterobifunctional Crosslinkers

6-(4-Azido-2-nitrophenylamino)hexanoic acid N-hydroxysuccinimide ester is a heterobifunctional compound featuring an azide and a succinimidyl ester moiety. The azide group enables click chemistry reactions, particularly with alkynes, facilitating rapid and selective conjugation. Meanwhile, the N-hydroxysuccinimide ester promotes efficient coupling with amines, allowing for the formation of stable linkages. This unique combination of functionalities supports intricate molecular designs and enhances the versatility of bioconjugation strategies.

N-Succinimidyloxycarbonylpentyl Methanethiosulfonate is a heterobifunctional reagent characterized by its distinct thiol-reactive and amine-reactive functionalities. The methanethiosulfonate group enables selective conjugation with thiols, forming stable thioether bonds, while the succinimidyl moiety facilitates efficient coupling with amines. This dual reactivity allows for precise manipulation of biomolecules, enabling complex assembly and modification in various biochemical applications.

4-(Maleimido)benzophenone is a heterobifunctional compound featuring a maleimide group that selectively reacts with thiols, forming stable thioether linkages. Its benzophenone moiety enhances photochemical properties, allowing for light-induced reactions. This compound exhibits unique reactivity profiles, enabling the formation of covalent bonds under mild conditions. The distinct spatial arrangement of its functional groups facilitates targeted modifications, making it a versatile tool in bioconjugation strategies.

Sulphosuccinimidyl 6-(4'-azido-2'-nitrophenylamino)hexanoate is a heterobifunctional compound featuring an azido group and a sulfo-succinimidyl moiety. The azido group is highly reactive, enabling specific click reactions with alkynes, while the sulfo-succinimidyl component enhances the formation of stable amide bonds with primary amines. This dual reactivity allows for precise molecular modifications, promoting efficient conjugation and cross-linking in complex biochemical systems.

N-Succinimidyl 4-Azidosalicylate is a heterobifunctional reagent characterized by its azide and succinimidyl functionalities. The azide group enables efficient click chemistry, facilitating rapid and selective reactions with alkyne partners, while the succinimidyl moiety promotes amine coupling, enhancing conjugation efficiency. This compound's unique reactivity allows for versatile labeling and cross-linking applications, with the potential for minimal steric hindrance, ensuring effective molecular interactions in diverse environments.

4-Maleimidophenyl isocyanate is a heterobifunctional reagent characterized by its maleimide and isocyanate functionalities. The maleimide group selectively reacts with thiol-containing compounds, facilitating the formation of stable thioether linkages. Meanwhile, the isocyanate moiety exhibits high reactivity towards amines, enabling the formation of urea bonds. This dual reactivity allows for versatile conjugation strategies, enhancing the specificity and efficiency of molecular assembly in various applications.

N-Succinimidyl 6-[[4-(Maleimidomethyl)cyclohexyl]carboxamido] Caproate is a heterobifunctional compound featuring a succinimidyl ester and a maleimide group. The succinimidyl moiety exhibits a strong tendency to react with amines, forming stable amide bonds, while the maleimide selectively engages with thiols, creating robust thioether linkages. This unique dual reactivity facilitates precise molecular conjugation, enabling tailored interactions in complex biochemical environments.

S-[2-(4-Azidosalicylamido)ethylthio]-2-thiopyridine is a heterobifunctional compound characterized by its azide and thiopyridine functionalities. The azide group allows for efficient click chemistry reactions, particularly with alkynes, facilitating rapid and selective conjugation. Meanwhile, the thiopyridine moiety can engage in coordination with metal ions, enhancing its reactivity and enabling diverse pathways for molecular assembly. This dual reactivity supports intricate manipulation of molecular architectures in various contexts.

Sulfo-N-succinimidyl 6-[3-(2-Pyridyldithio)propionamido] Hexanoate, Sodium Salt is a heterobifunctional reagent featuring a sulfonate and a pyridyldithio group. The sulfonate enhances solubility and reactivity in aqueous environments, while the pyridyldithio moiety facilitates disulfide bond formation, enabling selective cross-linking with thiol-containing molecules. This unique combination allows for precise control over conjugation reactions, promoting complex biomolecular interactions and structural modifications.

S-[2-(Iodo-4-Azidosalicylamido)ethylthio]-2-thiopyridine is a heterobifunctional compound characterized by its iodo and azido functionalities, which enable versatile reactivity. The azido group allows for click chemistry applications, facilitating rapid and selective conjugation with alkyne-bearing partners. Meanwhile, the thiopyridine moiety enhances nucleophilicity, promoting unique interactions with electrophiles. This dual reactivity supports intricate molecular assembly and targeted modifications in complex systems.