HDAC3 Inhibitors
Santa Cruz Biotechnology now offers a broad range of HDAC3 Inhibitors. Histone deacetylase proteins (HDACs) are a class of enzymes that remove acetyl groups (O=C-CH3) from an <ε>-N-acetyl lysine amino acid on a histone, allowing histones to wrap DNA more tightly. The deacetylation of histones is associated with transcriptional silencing. Histone deacetylase inhibitors (HDIs) have a long history of use in psychiatry and neurology as mood stabilizers and anti-epileptic. HDIs are studied as a treatment for neurodegenerative diseases and have a potential for cancer therapy. HDAC3 Inhibitors offered by Santa Cruz inhibit HDAC3 and, in some cases, other chromatin remodeling and transcription regulation related proteins. View detailed HDAC3 Inhibitor specifications, including HDAC3 Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Tris Buffered Saline: 1 L of 1X | sc-362185 | 1 L | $21.00 | 3 | ||
Tubacin is a selective HDAC6 inhibitor, indirectly impacting HDAC3 activity. By modulating HDAC6, it influences cellular processes, including microtubule dynamics and aggresome formation. These changes can indirectly affect HDAC3-mediated deacetylation and chromatin structure, impacting gene expression regulated by HDAC3. | ||||||
TMP269 | 1314890-29-3 | sc-475375 | 5 mg | $340.00 | ||
TMP269 is a selective class I HDAC inhibitor, including HDAC3. By targeting the zinc-binding domain, it indirectly influences HDAC3-mediated deacetylation. This results in altered chromatin structure and gene expression, impacting cellular processes associated with HDAC3 function. | ||||||