Date published: 2026-5-25

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HADHA Activators

The chemicals listed above can indirectly activate HADHA through various mechanisms. Bezafibrate and fenofibrate are PPARα agonists that enhance the transcriptional activity of PPARα, leading to increased expression of genes involved in fatty acid metabolism, including HADHA. Resveratrol activates SIRT1, which can deacetylate and activate PGC-1α, a regulator of HADHA. Carnitine is an essential cofactor for the transport of long-chain fatty acids into the mitochondria, promoting HADHA activity. AMPK activators, such as metformin, caffeine, and quercetin, can modulate cellular energy status and metabolism, indirectly influencing HADHA function.

NAD+ supports HADHA enzymatic activity by participating in redox reactions. Acetyl-L-carnitine enhances mitochondrial function, potentially stimulating HADHA activity. Omega-3 fatty acids affect gene expression and cellular metabolism, potentially impacting HADHA. Curcumin activates AMPK and induces mitochondrial biogenesis, while bezafibrate and fenofibrate are PPARα agonists that enhance the transcriptional activity of PPARα, leading to increased HADHA expression. These chemicals can indirectly activate HADHA by influencing signaling pathways and cellular processes involved in fatty acid metabolism and mitochondrial function.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Bezafibrate

41859-67-0sc-204650B
sc-204650
sc-204650A
sc-204650C
500 mg
1 g
5 g
10 g
$31.00
$46.00
$122.00
$204.00
5
(1)

Bezafibrate is a PPARα agonist that can potentially activate HADHA indirectly by enhancing the transcriptional activity of PPARα.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol is a natural compound that can activate SIRT1, which in turn can deacetylate and activate PGC-1α, a regulator of HADHA.

L-Carnitine

541-15-1sc-205727
sc-205727A
sc-205727B
sc-205727C
1 g
5 g
100 g
250 g
$23.00
$34.00
$79.00
$179.00
3
(1)

Carnitine is an essential cofactor for the transport of long-chain fatty acids into the mitochondria, promoting HADHA activity.

NAD+, Free Acid

53-84-9sc-208084B
sc-208084
sc-208084A
sc-208084C
sc-208084D
sc-208084E
sc-208084F
1 g
5 g
10 g
25 g
100 g
1 kg
5 kg
$57.00
$191.00
$302.00
$450.00
$1800.00
$3570.00
$10710.00
4
(2)

NAD+ is a coenzyme involved in redox reactions and can indirectly activate HADHA by supporting its enzymatic function.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

Quercetin is a flavonoid that can activate AMPK, indirectly promoting HADHA activity through the AMPK pathway.

Metformin

657-24-9sc-507370
10 mg
$79.00
2
(0)

Metformin is an AMPK activator that can indirectly activate HADHA by enhancing AMPK signaling and cellular energy metabolism.

Caffeine

58-08-2sc-202514
sc-202514A
sc-202514B
sc-202514C
sc-202514D
50 g
100 g
250 g
1 kg
5 kg
$33.00
$67.00
$97.00
$192.00
$775.00
13
(1)

Caffeine can activate AMPK and promote mitochondrial biogenesis, potentially influencing HADHA function indirectly.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin is a natural compound that can activate AMPK and induce mitochondrial biogenesis, potentially affecting HADHA activity.