Date published: 2025-12-19

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H2-M1 Inhibitors

H2-M1 inhibitors are a specific class of chemical compounds designed to modulate the activity of the H2-M1 protein. H2-M1, also known as histocompatibility 2, M region locus 1, is a protein that is part of the major histocompatibility complex (MHC) in mice, which plays a critical role in the immune system. The primary function of H2-M1 is to present antigenic peptides to T cells, facilitating the recognition of foreign pathogens by the immune system. This process is essential for the body's ability to mount an immune response against infections. H2-M1 inhibitors are developed with the primary goal of selectively interacting with the H2-M1 protein, potentially influencing its antigen-presenting activity and, consequently, impacting the immune response against specific antigens.

Typically, H2-M1 inhibitors consist of small molecules or chemical compounds specifically designed to bind to H2-M1, targeting either its active site or allosteric sites. This interaction can lead to the modulation of H2-M1's behavior, potentially affecting its ability to present antigenic peptides to T cells. Researchers are primarily interested in elucidating the molecular mechanisms and functions of H2-M1 in the context of antigen presentation and immune response. The development of H2-M1 inhibitors represents an ongoing area of research within the field of immunology and molecular pharmacology, contributing to our understanding of the immune system and its role in recognizing and defending against foreign invaders.

SEE ALSO...

Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$214.00
$316.00
$418.00
7
(1)

Decitabine can be incorporated into DNA, where it inhibits DNA methyltransferases, potentially leading to the demethylation and suppression of gene expression.

Hydralazine-15N4 Hydrochloride

304-20-1 (unlabeled)sc-490605
1 mg
$480.00
(0)

Hydralazine is hypothesized to inhibit DNA methylation, which might result in the altered expression of genes through epigenetic mechanisms.

RG 108

48208-26-0sc-204235
sc-204235A
10 mg
50 mg
$128.00
$505.00
2
(1)

RG108 is a non-nucleoside DNA methyltransferase inhibitor, which may prevent methylation of gene promoters, influencing gene expression levels.

Zebularine

3690-10-6sc-203315
sc-203315A
sc-203315B
10 mg
25 mg
100 mg
$126.00
$278.00
$984.00
3
(1)

Zebularine acts as a cytidine analog that inhibits DNA methyltransferase, potentially reducing gene expression through DNA demethylation.

Disulfiram

97-77-8sc-205654
sc-205654A
50 g
100 g
$52.00
$87.00
7
(1)

Disulfiram can modulate the activity of nucleic acid-related enzymes, potentially affecting transcription and gene expression.

Caffeic acid phenethyl ester

104594-70-9sc-200800
sc-200800A
sc-200800B
20 mg
100 mg
1 g
$70.00
$290.00
$600.00
19
(1)

This compound has been shown to inhibit NF-κB, which could downregulate genes involved in immune responses.

Sinefungin

58944-73-3sc-203263
sc-203263B
sc-203263C
sc-203263A
1 mg
100 mg
1 g
10 mg
$266.00
$5100.00
$39576.00
$690.00
4
(1)

Sinefungin is an adenosine analog that can inhibit methyltransferase enzymes, potentially affecting gene expression regulation.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$26.00
$92.00
$120.00
$310.00
$500.00
$908.00
$1821.00
46
(1)

Genistein is a tyrosine kinase inhibitor that may also affect DNA methylation and histone acetylation, altering gene expression.

Parthenolide

20554-84-1sc-3523
sc-3523A
50 mg
250 mg
$79.00
$300.00
32
(2)

Parthenolide can inhibit NF-κB, which may decrease the transcription of certain genes involved in immune regulation.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$108.00
$245.00
$918.00
$49.00
33
(2)

Quercetin is known to modulate several signaling pathways and may influence gene expression by affecting transcription factor activity.