Date published: 2026-1-22

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GCL Antibodies

Santa Cruz Biotechnology features a diverse variety of GCL Antibodies for investigating glutamate-cysteine ligase (GCL) in cellular processes. GCL Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Glutamate-cysteine ligase functions as a key enzyme in glutathione synthesis, an essential antioxidant protecting cells from oxidative stress. GCL maintains cellular defense mechanisms through regulation of intracellular glutathione levels, supporting detoxification and redox balance. Research focused on GCL continues to reveal its significance in neurodegenerative disorders and cancer development. Understanding glutamate-cysteine ligase activity provides valuable insights into cellular protection mechanisms and potential therapeutic approaches. Investigating GCL expression patterns helps identify its role in various pathological conditions. Santa Cruz Biotechnology monoclonal antibodies enable researchers to advance scientific understanding of glutamate-cysteine ligase, contributing to breakthrough discoveries in biomedical research.

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GCL Antibodies

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GCL Antibody (B-4)

sc-271330mouse IgG1 κ457-511 (h)WB, IP, IF, ELISAh
1
(1)

GCL siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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GCL siRNA (h)

sc-72182hGene SilencingN/A0
(0)

GCL shRNA Plasmid (h)

sc-72182-SHhGene SilencingPuromycin0
(0)

GCL shRNA (h) Lentiviral Particles

sc-72182-VhGene SilencingPuromycin0
(0)

GCL siRNA (m)

sc-72183mGene SilencingN/A0
(0)

GCL shRNA Plasmid (m)

sc-72183-SHmGene SilencingPuromycin0
(0)

GCL shRNA (m) Lentiviral Particles

sc-72183-VmGene SilencingPuromycin0
(0)