GalNAc-T Substrates

Santa Cruz Biotechnology now offers a broad range of GalNAc-T Substrates for use in various applications. GalNAc transferases (GalNAc-Ts) are a family of enzymes that play a crucial role in the O-glycosylation of proteins, a process where N-acetylgalactosamine (GalNAc) is transferred to serine or threonine residues on proteins. This modification is essential for the proper function, stability, and localization of many proteins, and is involved in numerous biological processes, including cell signaling, immune response, and the maintenance of cell structure. GalNAc-T Substrates are indispensable tools in scientific research, enabling the detailed study of enzyme specificity, activity, and the broader implications of O-glycosylation in cellular processes. Researchers use these substrates in enzymatic assays to explore the kinetics of GalNAc-Ts, to investigate the role of specific glycosylation patterns in protein function, and to understand how dysregulation of these enzymes can contribute to diseases such as cancer and congenital disorders of glycosylation. Additionally, GalNAc-T Substrates are valuable in the development of scientific strategies aimed at modulating glycosylation patterns for disease treatment. The availability of these substrates has significantly advanced research in fields such as biochemistry, molecular biology, and glycobiology, offering critical insights into the complex processes of protein modification and their impact on health and disease. View detailed information on our available GalNAc-T Substrates by clicking on the product name.