Date published: 2025-10-16

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GABA Receptor Substrates

Santa Cruz Biotechnology now offers a broad range of GABA Receptor Substrates for use in various applications. GABA Receptor Substrates are essential compounds used in neuroscience research to study the function and regulation of gamma-aminobutyric acid (GABA) receptors, which are pivotal for mediating inhibitory neurotransmission in the central nervous system. These substrates play a crucial role in helping scientists understand the detailed mechanisms of synaptic transmission and neuronal communication. By interacting with GABA receptors, these substrates allow researchers to explore the dynamic processes of receptor activation and inhibition, providing insights into how GABAergic signaling maintains the balance between neuronal excitation and inhibition. GABA Receptor Substrates are instrumental in investigating the structural and functional properties of GABA receptors, including their subunit composition, binding sites, and conformational changes during receptor activity. Utilizing these substrates, researchers can study the effects of various modulatory factors on GABA receptor function, shedding light on the intricate regulatory mechanisms that control neural network dynamics and overall brain function. Additionally, GABA Receptor Substrates are employed in electrophysiological studies to measure changes in membrane potential and ion flux, offering a deeper understanding of the biophysical properties of GABA receptor channels. These substrates are also used in high-throughput screening assays to identify novel compounds that interact with GABA receptors, thus broadening the scope of receptor research. The data obtained from studies using GABA Receptor Substrates are fundamental for advancing knowledge in the fields of neurobiology and biochemistry, contributing to a comprehensive understanding of inhibitory neurotransmission and the regulation of neural activity. View detailed information on our available GABA Receptor Substrates by clicking on the product name.

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Items 11 to 12 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

U 90042

134516-99-7sc-204362
sc-204362A
10 mg
50 mg
$155.00
$620.00
(0)

U 90042 acts as a potent GABA receptor modulator, distinguished by its capacity to induce conformational changes in the receptor structure. This compound exhibits unique binding affinity, facilitating enhanced chloride ion permeability through the receptor channel. Its reaction kinetics suggest a rapid onset of action, influencing downstream signaling cascades. Additionally, U 90042's hydrophobic characteristics may promote interactions with membrane lipid bilayers, potentially altering receptor localization and function.

TCS 1205

355022-97-8sc-358561
sc-358561A
10 mg
50 mg
$138.00
$607.00
(0)

TCS 1205 functions as a selective GABA receptor modulator, characterized by its ability to stabilize specific receptor conformations. This compound demonstrates a unique interaction profile, enhancing the receptor's affinity for GABA and promoting increased ion flow. Its kinetic properties indicate a gradual modulation of receptor activity, influencing synaptic transmission dynamics. Furthermore, TCS 1205's amphipathic nature may facilitate its integration into lipid environments, impacting receptor clustering and signaling pathways.