FXR1 Inhibitors
FXR1 inhibitors constitute a chemical class of compounds specifically designed to selectively and reversibly target FXR1 (Fragile X-related 1), an RNA-binding protein with diverse roles in cellular processes, including RNA metabolism and translational regulation. These inhibitors are meticulously engineered to interact with FXR1, potentially modulating its RNA-binding activity and its involvement in translational control.
The chemical structure of FXR1 inhibitors enables them to bind to specific regions or binding sites on FXR1, interfering with its ability to interact with RNA targets. As a result, FXR1 inhibitors have been employed in biochemical and cellular studies to elucidate FXR1's functions and its contributions to various cellular processes. The design and optimization of these inhibitors rely on a comprehensive understanding of FXR1's structural features and its role in RNA biology, providing essential tools for advancing research in the field of post-transcriptional gene regulation and cellular homeostasis.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Sirolimus is a macrolide compound known to inhibit mTOR (mammalian target of rapamycin) signaling, which indirectly affects FXR1 function. | ||||||
CX-5461 | 1138549-36-6 | sc-507275 | 5 mg | $240.00 | ||
This compound is a selective inhibitor of RNA polymerase I transcription and has been shown to affect the expression of certain RNA-binding proteins, including FXR1. | ||||||
Honokiol | 35354-74-6 | sc-202653 sc-202653A | 10 mg 25 mg | $118.00 $178.00 | 4 | |
A natural compound found in the bark of the magnolia tree, Honokiol has been reported to inhibit FXR1 function. | ||||||
PNU-74654 | 113906-27-7 | sc-258020 sc-258020A | 5 mg 25 mg | $128.00 $485.00 | 7 | |
A synthetic compound that has been identified as a potential inhibitor of FXR1 and other RNA-binding proteins. | ||||||
Trifluoperazine Dihydrochloride | 440-17-5 | sc-201498 sc-201498A | 1 g 5 g | $56.00 $99.00 | 9 | |
Originally developed as an antipsychotic drug, Trifluoperazine has been reported to inhibit FXR1 function. | ||||||
Ciclopirox | 29342-05-0 | sc-217893 | 25 mg | $207.00 | 2 | |
Ciclopirox is an antifungal agent that has been identified as a potential inhibitor of FXR1. | ||||||
Xanthohumol from hop (Humulus lupulus) | 6754-58-1 | sc-301982 | 5 mg | $354.00 | 1 | |
A flavonoid compound found in hops, Xanthohumol has been reported to inhibit FXR1 function in certain cellular contexts. | ||||||
Cdc2-Like Kinase Inhibitor, TG003 | 300801-52-9 | sc-202528 sc-202528A | 5 mg 25 mg | $136.00 $537.00 | 6 | |
This compound is a selective inhibitor of CLK (CDC-like kinase) family of kinases, which are involved in RNA splicing and have been reported to affect FXR1 function. | ||||||
Rocaglamide | 84573-16-0 | sc-203241 sc-203241A sc-203241B sc-203241C sc-203241D | 100 µg 1 mg 5 mg 10 mg 25 mg | $270.00 $465.00 $1607.00 $2448.00 $5239.00 | 4 | |
Rocaglamide is a natural compound found in the Aglaia tree genus, and it has been identified as a potential inhibitor of FXR1. | ||||||