FK506 Antibodies

Santa Cruz Biotechnology features a diverse variety of FK506 monoclonal antibodies for research focused on understanding FK506's role in various biological processes. FK506 monoclonal antibodies are suitable for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). FK506, also known as Tacrolimus, is a potent immunosuppressant that inhibits T-cell activation and is widely used in organ transplantation to prevent rejection. It functions by binding to FKBP12, leading to the inhibition of calcineurin and subsequent downregulation of interleukin-2 production, which is crucial for T-cell proliferation. Understanding the mechanisms of FK506 is essential for improving therapeutic strategies in transplant medicine and autoimmune diseases. FK506 monoclonal antibodies enable researchers to explore cellular pathways and protein interactions involved in immunosuppression. Studying FK506's molecular mechanisms can reveal new therapeutic targets and improve treatment strategies. Research with FK506 monoclonal antibodies has advanced understanding of transplant rejection and autoimmune conditions. Santa Cruz Biotechnology monoclonal antibodies support scientific advancement by enabling detailed investigation of FK506-mediated immunosuppression pathways.