FHL-2 Activators
The class of FHL-2 activators encompasses a diverse array of chemicals that modulate the function of FHL-2, a protein involved in various cellular processes. These activators either directly target FHL-2 or act indirectly by influencing specific signaling pathways associated with FHL-2. AICAR (Acadesine), Resveratrol, Metformin, GW501516 (Cardarine), Quercetin, A769662, Oxytocin, Betaine, NAD+ (Nicotinamide adenine dinucleotide), Berberine, Epigallocatechin Gallate (EGCG), and FK866 (Apoptozole) represent a selection of chemicals with the ability to activate FHL-2 or its associated pathways. AICAR, Resveratrol, Metformin, Quercetin, and Berberine are activators of AMP-activated protein kinase (AMPK), a key player in cellular energy regulation. These chemicals can influence FHL-2-mediated processes related to energy homeostasis, cell growth, and metabolism.
GW501516 (Cardarine) is a peroxisome proliferator-activated receptor-delta (PPAR-δ) agonist, activating pathways associated with metabolism and inflammation. This chemical offers a tool to explore the impact of PPAR-δ activation on FHL-2 function. Oxytocin, a neuropeptide hormone, can activate its receptor, influencing FHL-2-mediated pathways related to social behavior and stress response. Betaine, NAD+, and FK866 (Apoptozole) operate indirectly by modulating pathways involved in methylation, redox reactions, and NAD+ availability, respectively. These chemicals can impact FHL-2 function in processes such as gene expression, aging, and stress response. The remaining chemicals, A769662, Epigallocatechin Gallate (EGCG), and FK866 (Apoptozole), contribute to FHL-2 modulation through various pathways, including AMPK, sirtuin activation, and NAD+ depletion, offering a range of tools for investigating FHL-2 dynamics in cellular processes. Researchers can leverage these activators to unravel the intricate regulatory mechanisms of FHL-2, gaining insights into its role in normal cellular physiology and disease states. The specific targeting of FHL-2 or its associated pathways allows for detailed investigations into the functional aspects of FHL-2, providing valuable tools for advancing our understanding of cellular dynamics.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) is an activator of AMP-activated protein kinase (AMPK). FHL-2 has been associated with AMPK signaling pathways, and AICAR can activate AMPK, leading to the modulation of FHL-2-mediated cellular processes. This activation influences FHL-2 involvement in energy homeostasis, cell proliferation, and metabolism. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol is a polyphenolic compound found in red wine and grapes. It is known to activate the Sirtuin 1 (SIRT1) pathway. FHL-2 interacts with SIRT1, and Resveratrol activates SIRT1, influencing FHL-2-mediated pathways. This activation affects FHL-2 involvement in cellular processes related to metabolism, inflammation, and longevity. Resveratrol provides a tool to investigate the specific impact of SIRT1 activation on FHL-2 function and cellular dynamics. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $77.00 | 2 | |
Metformin is an antidiabetic drug that activates AMP-activated protein kinase (AMPK). FHL-2 has connections with AMPK signaling, and Metformin's activation of AMPK influences FHL-2-mediated cellular processes. This activation impacts FHL-2 involvement in energy regulation, cell growth, and metabolism. Metformin serves as a tool to explore the specific impact of AMPK activation on FHL-2 function and cellular dynamics. | ||||||
GW501516 | 317318-70-0 | sc-202642 sc-202642A | 1 mg 5 mg | $80.00 $175.00 | 28 | |
GW501516 is a peroxisome proliferator-activated receptor-delta (PPAR-δ) agonist. FHL-2 interacts with PPAR-δ, and GW501516 activation of PPAR-δ influences FHL-2-mediated pathways. This activation affects FHL-2 involvement in cellular processes related to metabolism, energy homeostasis, and inflammation. GW501516 provides a tool to investigate the specific impact of PPAR-δ activation on FHL-2 function and cellular dynamics. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin is a flavonoid that activates AMP-activated protein kinase (AMPK). FHL-2 is associated with AMPK signaling, and Quercetin's activation of AMPK influences FHL-2-mediated cellular processes. This activation affects FHL-2 involvement in energy homeostasis, cell growth, and metabolism. Quercetin serves as a tool to explore the specific impact of AMPK activation on FHL-2 function and cellular dynamics. | ||||||
A-769662 | 844499-71-4 | sc-203790 sc-203790A sc-203790B sc-203790C sc-203790D | 10 mg 50 mg 100 mg 500 mg 1 g | $180.00 $726.00 $1055.00 $3350.00 $5200.00 | 23 | |
A769662 is a direct activator of AMP-activated protein kinase (AMPK). FHL-2 has links to AMPK signaling, and A769662 activation of AMPK influences FHL-2-mediated cellular processes. This activation affects FHL-2 involvement in energy regulation, cell growth, and metabolism. A769662 provides a tool to investigate the specific impact of direct AMPK activation on FHL-2 function and cellular dynamics. | ||||||
Oxytocin acetate salt | 50-56-6 | sc-279938 sc-279938A sc-279938B sc-279938C sc-279938D sc-279938E | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $59.00 $176.00 $330.00 $650.00 $950.00 $1800.00 | 4 | |
Oxytocin is a neuropeptide hormone that activates the oxytocin receptor. FHL-2 has been implicated in pathways related to neuropeptide signaling. Oxytocin activation of its receptor influences FHL-2-mediated pathways, impacting cellular processes related to social behavior and stress response. Oxytocin serves as a tool to investigate the specific impact of neuropeptide receptor activation on FHL-2 function and cellular dynamics. | ||||||
Betaine | 107-43-7 | sc-214595 sc-214595A sc-214595B sc-214595C sc-214595D sc-214595E | 50 g 100 g 250 g 1 kg 2.5 kg 5 kg | $30.00 $40.00 $55.00 $160.00 $330.00 $580.00 | 2 | |
Betaine is a naturally occurring compound that influences methylation pathways. FHL-2 is involved in processes related to epigenetic regulation. Betaine's modulation of methylation pathways indirectly influences FHL-2-mediated cellular processes, impacting gene expression and cellular function. Betaine serves as a tool to explore the specific impact of methylation pathway modulation on FHL-2 function and cellular dynamics. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $56.00 $186.00 $296.00 $655.00 $2550.00 $3500.00 $10500.00 | 4 | |
NAD+ is a coenzyme involved in cellular redox reactions and a substrate for sirtuin enzymes. FHL-2 interacts with sirtuin enzymes, and NAD+ can indirectly activate sirtuins, influencing FHL-2-mediated pathways. This activation affects FHL-2 involvement in cellular processes related to metabolism, aging, and stress response. NAD+ serves as a tool to investigate the specific impact of sirtuin activation on FHL-2 function and cellular dynamics. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $90.00 | 1 | |
Berberine is a plant-derived compound that activates AMP-activated protein kinase (AMPK). FHL-2 is associated with AMPK signaling, and Berberine's activation of AMPK influences FHL-2-mediated cellular processes. This activation affects FHL-2 involvement in energy homeostasis, cell growth, and metabolism. Berberine serves as a tool to explore the specific impact of AMPK activation on FHL-2 function and cellular dynamics. | ||||||