FBXO24 Activators

FBXO24, or F-box protein 24, is a protein that in humans is encoded by the FBXO24 gene. It's a member of the F-box protein family, characterized by an approximately 40 amino acid motif known as the F-box, which is a critical component of the SKP1-CUL1-F-box protein (SCF) E3 ubiquitin ligase complex.The SCF complex plays a key role in protein degradation, a fundamental process in cells. It's responsible for the ubiquitination of proteins, a process that tags them for degradation by the 26S proteasome. This means that FBXO24, as part of this complex, participates in the regulation of protein levels within the cell. This affects a wide array of cellular processes such as cell cycle progression, signal transduction, and stress response.

There are indications that FBXO24 might be involved in various pathological conditions, including cancer. Some studies suggest that FBXO24 could function as a tumor suppressor, as it has been implicated in the degradation of MYC, a protein often overexpressed in many types of cancer.In summary, FBXO24 is a member of the F-box protein family and plays a role in protein degradation as part of the SCF E3 ubiquitin ligase complex. Its potential involvement in cancer, possibly through the degradation of MYC, makes it an interesting target for further research in cancer biology. However, much remains to be discovered about the precise functions and targets of FBXO24.