FATE1 Inhibitors
FATE1 inhibitors predominantly target cellular pathways that may interact or intersect with FATE1's role in cellular development and function. While direct inhibition of FATE1 remains elusive, modulating the signaling cascades that surround its functional milieu offers potential for indirect control over its activity. Kinase inhibitors such as Staurosporine present broad-spectrum action, influencing a myriad of signaling cascades which might intersect with FATE1's role. Furthermore, the PI3K pathway, modulated by inhibitors like Wortmannin and LY294002, plays a pivotal role in cellular signaling and might provide an avenue for indirect FATE1 modulation.
Another pathway of interest is the MAPK pathway, targeted by PD98059, U0126, and SB203580. Given that FATE1 is linked to cellular development and function, dampening or modulating this pathway might yield implications for FATE1's activity. The intricacies of cellular calcium dynamics, influenced by agents like 2-APB, Ionomycin, BAPTA-AM, and Thapsigargin, underscore the importance of intracellular signaling in shaping the functional landscape of proteins like FATE1.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Kinase inhibitor known to affect various signaling cascades. Its broad-spectrum inhibition can alter pathways potentially interacting with FATE1. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
PI3K inhibitor. Given that PI3K pathways can be involved in cellular development and function, FATE1 could be indirectly modulated. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Another PI3K inhibitor. Affecting the PI3K pathway can indirectly modulate proteins involved in similar cellular processes as FATE1. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor. JNK pathways play roles in cellular development, which might overlap with FATE1's function. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
MEK inhibitor that dampens the MAPK pathway. Given that FATE1 is involved in cellular function, MAPK modulation can influence FATE1 indirectly. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
Inhibits p38 MAPK, another pathway linked to cellular function and development. This could indirectly influence FATE1. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
mTOR inhibitor. By inhibiting mTOR, it affects cellular growth and function which might indirectly affect FATE1. | ||||||
2-APB | 524-95-8 | sc-201487 sc-201487A | 20 mg 100 mg | $27.00 $52.00 | 37 | |
Affects IP3 receptor-mediated calcium signaling. Calcium pathways can influence numerous cellular functions and may intersect with FATE1's role. | ||||||
Ionomycin, free acid | 56092-81-0 | sc-263405 sc-263405A | 1 mg 5 mg | $94.00 $259.00 | 2 | |
Calcium ionophore that modulates intracellular calcium levels. Indirect modulation of calcium might intersect with FATE1 functions. | ||||||
BAPTA/AM | 126150-97-8 | sc-202488 sc-202488A | 25 mg 100 mg | $138.00 $449.00 | 61 | |
Intracellular calcium chelator. Altering calcium dynamics can influence numerous proteins, potentially including FATE1. | ||||||