Date published: 2026-2-11

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Farnesyl Transferase Inhibitors

Santa Cruz Biotechnology now offers a broad range of Farnesyl Transferase Inhibitors for use in various applications. Farnesyl Transferase Inhibitors target the enzyme farnesyl transferase, which plays a critical role in the post-translational modification of proteins through farnesylation. This modification is essential for the proper functioning of various proteins that control cell division, signaling, and growth. By inhibiting this enzyme, researchers can study the impact of disrupted farnesylation on cellular processes, providing valuable insights into the molecular mechanisms that govern cell proliferation and differentiation. The use of Farnesyl Transferase Inhibitors has been instrumental in the field of biochemistry and cell biology, particularly in understanding how protein modifications affect cell behavior and contribute to the development of complex diseases. These inhibitors are also used to explore the pathways involved in protein localization and membrane association, areas critical for the functioning of signal transduction pathways. Additionally, the study of these inhibitors helps elucidate the role of protein prenylation in maintaining cellular integrity and response to external stimuli. This research is pivotal in uncovering the fundamental processes that underlie cellular adaptation and survival, particularly in response to metabolic and environmental changes. By providing these inhibitors, Santa Cruz Biotechnology enables a deeper exploration of cellular dynamics and protein interactions, enhancing our understanding of cellular regulation and the potential dysregulation. View detailed information on our available Farnesyl Transferase Inhibitors by clicking on the product name.

Items 11 to 12 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

FPT Inhibitor II

sc-221626
1 mg
$191.00
1
(0)

FPT Inhibitor II functions as a Farnesyl Transferase inhibitor by engaging in specific non-covalent interactions with the enzyme's active site. Its unique structural features facilitate a conformational change in the enzyme, hindering substrate access. The compound exhibits a distinct binding affinity, characterized by rapid association and slower dissociation rates, which enhances its inhibitory potency. Additionally, its hydrophobic regions contribute to selective enzyme targeting, influencing cellular localization and interaction dynamics.

Tipifarnib

192185-72-1sc-364637
10 mg
$720.00
(0)

Tipifarnib acts as a Farnesyl Transferase inhibitor by selectively binding to the enzyme's active site, disrupting the farnesylation process. Its unique molecular architecture allows for specific hydrogen bonding and hydrophobic interactions, stabilizing the enzyme-inhibitor complex. The compound demonstrates a notable kinetic profile, with a fast initial binding phase followed by a gradual equilibrium, which enhances its effectiveness in modulating enzyme activity. Its distinct physicochemical properties further influence its solubility and distribution within biological systems.